Genetic drugs based on RNA or DNA have remarkable therapeutic potential as virtually any
disease can be treated by silencing a pathological gene, expressing a beneficial protein, or …

Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

Conventional forms of drug administration generally rely on pills, eye drops, ointments, and
intravenous solutions. Recently, a number of novel drug delivery approaches have been …

Advances in directed evolution and membrane biophysics make the synthesis of simple
living cells, if not yet foreseeable reality, an imaginable goal. Overcoming the many scientific …

The toxicity of amyloid‐forming proteins is correlated with their interactions with cell
membranes. Binding events between amyloidogenic proteins and membranes result in …

Supramolecular binary vesicles based on the host–guest complexation of water-soluble
pillar [6] arene (WP6) and SAINT molecule have been successfully constructed, which …

In response to many apoptotic stimuli, oligomerization of Bax is essential for mitochondrial
outer membrane permeabilization and the ensuing release of cytochrome c. These events …

Ceragenins are cationic bile salt derivatives having antimicrobial activity. The interactions of
several ceragenins with phospholipid bilayers were tested in different systems. The …

Pore-forming toxins (PFT) are water-soluble proteins that possess the remarkable ability to
self-assemble on the membrane of target cells, where they form pores causing cell damage …

Strategies used to enhance liposome-mediated drug delivery in vivo include the
enhancement of stability and circulation time in the bloodstream, targeting to specific tissues …