Circulating adipokines and inflammatory markers and postmenopausal breast cancer risk

MJ Gunter, T Wang, M Cushman, X Xue… - Journal of the …, 2015 - academic.oup.com
Background: Adipokines and inflammation may provide a mechanistic link between obesity
and postmenopausal breast cancer, yet epidemiologic data on their associations with breast …

Hyperthyroidism, hypothyroidism, and cause-specific mortality in a large cohort of women

NMY Journy, MO Bernier, MM Doody, BH Alexander… - Thyroid, 2017 - liebertpub.com
Background: The prevalence of hyperthyroidism and hypothyroidism is 0.5–4% in iodine-
replete communities, but it is 5–10 times higher in women than in men. Those conditions are …

Associations of hyperglycemia and insulin usage with the risk of cancer in type 2 diabetes: the Hong Kong diabetes registry

X Yang, GTC Ko, WY So, RCW Ma, LWL Yu… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Insulin has mitogenic effects, although hyperglycemia may be a risk factor for
cancer in type 2 diabetes. It remains uncertain whether use of insulin increases cancer risk …

[HTML][HTML] SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia

AR Nasiri, MR Rodrigues, Z Li, BP Leitner… - Cancer & Metabolism, 2019 - Springer
Background Obesity confers an increased risk and accelerates the progression of multiple
tumor types in rodents and humans, including both breast and colon cancer. Because …

[HTML][HTML] New therapies for advanced, recurrent, and metastatic endometrial cancers

V Makker, AK Green, RM Wenham, D Mutch… - … oncology research and …, 2017 - Springer
Endometrial cancer is the most common gynecologic malignancy in the United States,
accounting for 6% of cancers in women. In 2017, an estimated 61,380 women were …

Obesity and breast cancer: molecular interconnections and potential clinical applications

V Simone, M D'avenia, A Argentiero, C Felici… - The …, 2016 - academic.oup.com
Obesity is an important risk factor for breast cancer (BC) in postmenopausal women;
interlinked molecular mechanisms might be involved in the pathogenesis. Increased levels …

[HTML][HTML] The association between obesity related adipokines and risk of breast cancer: a meta-analysis

Y Gui, Q Pan, X Chen, S Xu, X Luo, L Chen - Oncotarget, 2017 - ncbi.nlm.nih.gov
The risk of breast cancer is significantly increased among obese women as the deleterious
adipokines can be over secreted and beneficial adipokines can be hyposecreted. We aim to …

Hyperinsulinaemia and insulin signalling in the pathogenesis and the clinical course of hepatocellular carcinoma

H Chettouh, M Lequoy, L Fartoux… - Liver …, 2015 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the fifth most prevalent cancer and is one of the leading
causes of cancer‐related death. The risk factors for HCC include cirrhosis, chronic viral …

Association between markers of obesity and progression from Barrett's esophagus to esophageal adenocarcinoma

C Duggan, L Onstad, S Hardikar, PL Blount… - Clinical …, 2013 - Elsevier
Background & Aims Individuals with Barrett's esophagus (BE) have an increased risk of
developing esophageal adenocarcinoma (EA). Obesity contributes to the development of BE …

[HTML][HTML] Obesity, cancer risk, and time-restricted eating

M Das, NJG Webster - Cancer and Metastasis Reviews, 2022 - Springer
Obesity and the associated metabolic syndrome is considered a pandemic whose
prevalence is steadily increasing in many countries worldwide. It is a complex, dynamic, and …