Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment
RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …
functioning associated with the disorder and are not responsive to existing treatments. In this …
Towards a youth mental health paradigm: a perspective and roadmap
Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the
importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health …
importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health …
The lived experience of psychosis: a bottom‐up review co‐written by experts by experience and academics
P Fusar‐Poli, A Estradé, G Stanghellini… - World …, 2022 - Wiley Online Library
Psychosis is the most ineffable experience of mental disorder. We provide here the first co‐
written bottom‐up review of the lived experience of psychosis, whereby experts by …
written bottom‐up review of the lived experience of psychosis, whereby experts by …
Meta-analytic prevalence of comorbid mental disorders in individuals at clinical high risk of psychosis: the case for transdiagnostic assessment
Comorbid mental disorders in subjects at clinical high risk for psychosis (CHR-P) may
impact preventive care. We conducted a PRISMA/MOOSE-compliant systematic meta …
impact preventive care. We conducted a PRISMA/MOOSE-compliant systematic meta …
[HTML][HTML] Cognitive dysfunction in schizophrenia: an expert group paper on the current state of the art
Cognitive impairment in schizophrenia represents one of the main obstacles to clinical and
functional recovery. This expert group paper brings together experts in schizophrenia …
functional recovery. This expert group paper brings together experts in schizophrenia …
The course of general cognitive ability in individuals with psychotic disorders
K Jonas, W Lian, J Callahan, CJ Ruggero… - JAMA …, 2022 - jamanetwork.com
Importance Schizophrenia is associated with major cognitive deficits and has been
conceptualized as both a neurodevelopmental and a neurodegenerative disorder. However …
conceptualized as both a neurodevelopmental and a neurodegenerative disorder. However …
Arketamine for cognitive impairment in psychiatric disorders
K Hashimoto - European Archives of Psychiatry and Clinical …, 2023 - Springer
Cognitive impairment has been observed in patients with various psychiatric disorders,
including schizophrenia, major depressive disorder (MDD), and bipolar disorder (BD) …
including schizophrenia, major depressive disorder (MDD), and bipolar disorder (BD) …
Prevalence of individuals at clinical high-risk of psychosis in the general population and clinical samples: systematic review and meta-analysis
G Salazar de Pablo, SW Woods, G Drymonitou… - Brain sciences, 2021 - mdpi.com
(1) The consistency and magnitude of the prevalence of Clinical High-Risk for Psychosis
(CHR-P) individuals are undetermined, limiting efficient detection of cases. We aimed to …
(CHR-P) individuals are undetermined, limiting efficient detection of cases. We aimed to …
Schizophrenia: a developmental disorder with a risk of non-specific but avoidable decline
The onset of schizophrenia is determined by biological and social risk factors operating
predominantly during development. These result in subtle deviations in brain structure and …
predominantly during development. These result in subtle deviations in brain structure and …
Psychotic disorders as a framework for precision psychiatry
F Coutts, N Koutsouleris, P McGuire - Nature Reviews Neurology, 2023 - nature.com
People with psychotic disorders can show marked interindividual variations in the onset of
illness, responses to treatment and relapse, but they receive broadly similar clinical care …
illness, responses to treatment and relapse, but they receive broadly similar clinical care …