Macrophages: Their role, activation and polarization in pulmonary diseases
Macrophages, circulating in the blood or concatenated into different organs and tissues
constitute the first barrier against any disease. They are foremost controllers of both innate …
constitute the first barrier against any disease. They are foremost controllers of both innate …
[HTML][HTML] Recent developments in myofibroblast biology: paradigms for connective tissue remodeling
The discovery of the myofibroblast has opened new perspectives for the comprehension of
the biological mechanisms involved in wound healing and fibrotic diseases. In recent years …
the biological mechanisms involved in wound healing and fibrotic diseases. In recent years …
Pulmonary fibrosis: patterns and perpetrators
PW Noble, CE Barkauskas… - The Journal of clinical …, 2012 - Am Soc Clin Investig
Pulmonary fibrosis occurs in a variety of clinical settings, constitutes a major cause of
morbidity and mortality, and represents an enormous unmet medical need. However, the …
morbidity and mortality, and represents an enormous unmet medical need. However, the …
[PDF][PDF] Wnt/β-catenin signaling: a promising new target for fibrosis diseases.
Y Guo, L Xiao, L Sun, F Liu - Physiological research, 2012 - biomed.cas.cz
Wnt/β-Catenin Signaling: a Promising New Target for Fibrosis Diseases Page 1
PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) • ISSN 1802-9973(online) © 2012 …
PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) • ISSN 1802-9973(online) © 2012 …
miR-199a-5p Is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1
CL Lino Cardenas, IS Henaoui, E Courcot… - PLoS …, 2013 - journals.plos.org
As miRNAs are associated with normal cellular processes, deregulation of miRNAs is
thought to play a causative role in many complex diseases. Nevertheless, the precise …
thought to play a causative role in many complex diseases. Nevertheless, the precise …
miR-21 mediates nickel nanoparticle-induced pulmonary injury and fibrosis
Y Mo, Y Zhang, R Wan, M Jiang, Y Xu, Q Zhang - Nanotoxicology, 2020 - Taylor & Francis
We and other groups have demonstrated that exposure to nickel nanoparticles (Nano-Ni)
results in severe and persistent lung inflammation and fibrosis, but the underlying …
results in severe and persistent lung inflammation and fibrosis, but the underlying …
MicroRNA-153 physiologically inhibits expression of amyloid-β precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer …
Regulation of amyloid-β (Aβ) precursor protein (APP) expression is complex. MicroRNAs
(miRNAs) are expected to participate in the molecular network that controls this process. The …
(miRNAs) are expected to participate in the molecular network that controls this process. The …
Epigenetics of dementia: understanding the disease as a transformation rather than a state
Alzheimer's disease and other idiopathic dementias are associated with epigenetic
transformations. These transformations connect the environment and genes to …
transformations. These transformations connect the environment and genes to …
MicroRNA-34a regulates cardiac fibrosis after myocardial infarction by targeting Smad4
Y Huang, Y Qi, JQ Du, D Zhang - Expert opinion on therapeutic …, 2014 - Taylor & Francis
Background: Although few microRNAs (miRNAs) have been involved in the regulation of
post-ischemic cardiac fibrosis, the exact effect and underlying mechanism of miRNAs in …
post-ischemic cardiac fibrosis, the exact effect and underlying mechanism of miRNAs in …
Role of microRNAs in lung development and pulmonary diseases
MicroRNAs (miRNAs) are a class of small noncoding RNA which exert post-transcriptional
gene regulation activity by targeting messenger RNAs. miRNAs have been found to be …
gene regulation activity by targeting messenger RNAs. miRNAs have been found to be …