Mitochondria‐targeted nanoparticles in treatment of neurodegenerative diseases

Y Zhang, H Yang, D Wei, X Zhang, J Wang, X Wu… - …, 2021 - Wiley Online Library
Neurodegenerative diseases (NDs) are a class of heterogeneous diseases that includes
Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral …

[HTML][HTML] Nanomaterials in tumor immunotherapy: new strategies and challenges

X Zhu, S Li - Molecular Cancer, 2023 - Springer
Tumor immunotherapy exerts its anti-tumor effects by stimulating and enhancing immune
responses of the body. It has become another important modality of anti-tumor therapy with …

Long-acting PLGA microspheres: advances in excipient and product analysis toward improved product understanding

B Wan, Q Bao, D Burgess - Advanced Drug Delivery Reviews, 2023 - Elsevier
Poly (lactic-co-glycolic acid)(PLGA) microspheres are a sustained-release drug delivery
system with several successful commercial products used for the treatment of a variety of …

[HTML][HTML] Cell–scaffold interactions in tissue engineering for oral and craniofacial reconstruction

F Wang, X Cai, Y Shen, L Meng - Bioactive Materials, 2023 - Elsevier
Tissue engineering (TE) is critical in oral and craniofacial reconstruction. One of the most
popular topics on the biomaterial-based tissue regeneration process may be the interaction …

Responsive hydrogels based on triggered click reactions for liver cancer

JQ Zhu, H Wu, ZL Li, XF Xu, H Xing… - Advanced …, 2022 - Wiley Online Library
Globally, liver cancer, which is one of the major cancers worldwide, has attracted the
growing attention of technological researchers for its high mortality and limited treatment …

[HTML][HTML] Existing and novel biomaterials for bone tissue engineering

P Dec, A Modrzejewski, A Pawlik - International Journal of Molecular …, 2022 - mdpi.com
The treatment of bone defects remains one of the major challenges in modern clinical
practice. Nowadays, with the increased incidence of bone disease in an aging population …

[HTML][HTML] Glass transition temperature of PLGA particles and the influence on drug delivery applications

G Liu, K McEnnis - Polymers, 2022 - mdpi.com
Over recent decades, poly (lactic-co-glycolic acid)(PLGA) based nano-and micro-drug
delivery vehicles have been rapidly developed since PLGA was approved by the Food and …

Controlled release and targeted drug delivery with poly (lactic-co-glycolic acid) nanoparticles: reviewing two decades of research

A Zeb, M Gul, TTL Nguyen, HJ Maeng - Journal of Pharmaceutical …, 2022 - Springer
Background Controlled release and targeted delivery of the drug payload are the two most
fascinating applications of nanoparticle-based systems explored in the recent past. The …

Long-acting parenteral drug delivery systems for the treatment of chronic diseases

AB Jindal, AR Bhide, S Salave, D Rana… - Advanced Drug Delivery …, 2023 - Elsevier
The management of chronic conditions often requires patients to take daily medication for an
extended duration. However, the need for daily dosing can lead to nonadherence to the …

[HTML][HTML] Progress in the application of sustained-release drug microspheres in tissue engineering

L Ruan, M Su, X Qin, Q Ruan, W Lang, M Wu, Y Chen… - Materials Today Bio, 2022 - Elsevier
Sustained-release drug-loaded microspheres provide a long-acting sustained release, with
targeted and other effects. There are many types of sustained-release drug microspheres …