Tocilizumab in COVID-19: a study of adverse drug events reported in the WHO database

J Charan, S Dutta, R Kaur, P Bhardwaj… - Expert opinion on …, 2021 - Taylor & Francis
Background Elevated inflammatory cytokines in Coronavirus disease 2019 (COVID‐19)
affect the lungs leading to pneumonitis with a poor prognosis. Tocilizumab, a type of …

[HTML][HTML] Multinational Association of Supportive Care in Cancer (MASCC) 2020 clinical practice recommendations for the management of immune-related adverse …

VR Shannon, R Anderson, A Blidner, J Choi… - Supportive Care in …, 2020 - Springer
The immune checkpoints associated with the CTLA-4 and PD-1 pathways are critical
modulators of immune activation. These pathways dampen the immune response by …

[HTML][HTML] Deep learning algorithm trained with COVID-19 pneumonia also identifies immune checkpoint inhibitor therapy-related pneumonitis

CA Mallio, A Napolitano, G Castiello, FM Giordano… - Cancers, 2021 - mdpi.com
Simple Summary The use of immune checkpoint inhibitors (ICIs) to treat oncologic diseases
is progressively increasing. Computed tomography (CT) features of ICI therapy-related …

[HTML][HTML] Unbiased analysis of temporal changes in immune serum markers in acute COVID-19 infection with emphasis on organ failure, anti-viral treatment, and …

K Laudanski, H Jihane, B Antalosky, D Ghani… - Frontiers in …, 2021 - frontiersin.org
Identification of novel immune biomarkers to gauge the underlying pathology and severity of
COVID-19 has been difficult due to the lack of longitudinal studies. Here, we analyzed serum …

[HTML][HTML] Does immune checkpoint inhibitor increase the risks of poor outcomes in COVID-19-infected cancer patients? A systematic review and meta-analysis

G Lazarus, RA Budiman, I Rinaldi - Cancer Immunology, Immunotherapy, 2022 - Springer
Background The association between immune checkpoint inhibitor (ICI) and outcomes of
cancer patients with coronavirus disease 2019 (COVID-19) infection has yet to be …

[HTML][HTML] COVID-19 lung injury as a primer for immune checkpoint inhibitors (ICIs)-related pneumonia in a patient affected by squamous head and neck carcinoma …

A Dipasquale, P Persico, E Lorenzi… - … for Immunotherapy of …, 2021 - ncbi.nlm.nih.gov
By the beginning of the global pandemic, SARS-CoV-2 infection has dramatically impacted
on oncology daily practice. In the current oncological landscape, where immunotherapy has …

[HTML][HTML] Longitudinal urinary biomarkers of immunological activation in covid-19 patients without clinically apparent kidney disease versus acute and chronic failure

K Laudanski, T Okeke, J Hajj, K Siddiq, DJ Rader… - Scientific Reports, 2021 - nature.com
Kidney function is affected in COVID-19, while kidney itself modulates the immune response.
Here, hypothesize if COVID-19 urine biomarkers level can assess immune activation vs …

[HTML][HTML] Immune checkpoint inhibitor-related pneumonitis and COVID-19: a case-matched comparison of CT findings

R Picasso, A Cozzi, V Picasso, F Zaottini, F Pistoia… - La radiologia …, 2023 - Springer
Objectives To compare the radiological findings of immune checkpoint inhibitor-related
pneumonitis (IRP) and COVID-19 pneumonia, evaluating the potential of the CO-RADS …

A single center retrospective study of the impact of COVID-19 infection on immune-related adverse events in cancer patients receiving immune checkpoint inhibitors

M Guo, J Liu, R Miao, Z Ahmed, J Yu… - Journal of …, 2022 - journals.lww.com
Immune checkpoint inhibitors (ICIs) can cause a variety of immune-related adverse events
(irAEs). The coronavirus disease 2019 (COVID-19) is associated with increased amounts of …

[HTML][HTML] Clinical outcomes in COVID-19 patients treated with immunotherapy

H Hatic, KR Hearld, D Das, J Deshane - Cancers, 2022 - mdpi.com
Simple Summary Patients with cancer who contract COVID-19 are very vulnerable to
increased complications and illness while actively being treated with chemotherapy or …