Combatting the evolution of antifungal resistance in Cryptococcus neoformans

A Bermas, J Geddes‐McAlister - Molecular microbiology, 2020 - Wiley Online Library
Fungal infections are a global concern and the evolution of intrinsic resistance to current
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …

Melanin of fungi: From classification to application

R Liu, X Meng, C Mo, X Wei, A Ma - World Journal of Microbiology and …, 2022 - Springer
Melanin is a secondary metabolite composed of complex heterogeneous polymers. Fungal
melanin is considered to be a sustainable and biodegradable natural pigment and has a …

Mind the mushroom: natural product biosynthetic genes and enzymes of Basidiomycota

M Gressler, NA Löhr, T Schäfer, S Lawrinowitz… - Natural product …, 2021 - pubs.rsc.org
Covering: up to September 2020 Mushroom-forming fungi of the division Basidiomycota
have traditionally been recognised as prolific producers of structurally diverse and often …

Fungal pigments and their roles associated with human health

L Lin, J Xu - Journal of Fungi, 2020 - mdpi.com
Fungi can produce myriad secondary metabolites, including pigments. Some of these
pigments play a positive role in human welfare while others are detrimental. This paper …

The high osmolarity glycerol (HOG) pathway in fungi

H Yaakoub, NS Sanchez, L Ongay-Larios… - Critical Reviews in …, 2022 - Taylor & Francis
While fungi are widely occupying nature, many species are responsible for devastating
mycosis in humans. Such niche diversity explains how quick fungal adaptation is necessary …

The novel spore-specific regulator SscA controls Aspergillus conidiogenesis

YE Son, JH Yu, HS Park - Mbio, 2023 - Am Soc Microbiol
ABSTRACT A major group of fungi produces asexual spores (conidia) for dissemination and
propagation and, in pathogenic fungi, for infection. Despite the critical role of conidia, the …

Unraveling capsule biosynthesis and signaling networks in Cryptococcus neoformans

EH Jang, JS Kim, SR Yu, YS Bahn - Microbiology spectrum, 2022 - Am Soc Microbiol
The polysaccharide capsule of Cryptococcus neoformans—an opportunistic basidiomycete
pathogen and the major etiological agent of fungal meningoencephalitis—is a key virulence …

Fungal melanins that deteriorate paper cultural heritage: An overview

DS Nitiu, AC Mallo, MCN Saparrat - Mycologia, 2020 - Taylor & Francis
Paper-based works of art and documents of cultural importance kept in museums and
libraries can show notorious signs of deterioration, including foxing stains, caused by fungal …

Solid-state NMR spectroscopy identifies three classes of lipids in Cryptococcus neoformans melanized cell walls and whole fungal cells

C Chrissian, E Camacho, JE Kelly, H Wang… - Journal of Biological …, 2020 - ASBMB
A primary virulence-associated trait of the opportunistic fungal pathogen Cryptococcus
neoformans is the production of melanin pigments that are deposited into the cell wall and …

[HTML][HTML] Cryptococcus escapes host immunity: What do we know?

C Yang, Y Huang, Y Zhou, X Zang, H Deng… - Frontiers in Cellular …, 2022 - frontiersin.org
Cryptococcus is an invasive fungus that seriously endangers human life and health, with a
complex and well-established immune-escaping mechanism that interferes with the function …