Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency

Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …

[HTML][HTML] Photoinduced electron transfer (PeT) based fluorescent probes for cellular imaging and disease therapy

H Niu, J Liu, HM O'Connor, T Gunnlaugsson… - Chemical Society …, 2023 - pubs.rsc.org
Typical PeT-based fluorescent probes are multi-component systems where a fluorophore is
connected to a recognition/activating group by an unconjugated linker. PeT-based …

[HTML][HTML] Nanoparticles for cancer therapy: current progress and challenges

S Gavas, S Quazi, TM Karpiński - Nanoscale research letters, 2021 - Springer
Cancer is one of the leading causes of death and morbidity with a complex pathophysiology.
Traditional cancer therapies include chemotherapy, radiation therapy, targeted therapy, and …

Towards targeting of shared mechanisms of cancer metastasis and therapy resistance

F Weiss, D Lauffenburger, P Friedl - Nature Reviews Cancer, 2022 - nature.com
Resistance to therapeutic treatment and metastatic progression jointly determine a fatal
outcome of cancer. Cancer metastasis and therapeutic resistance are traditionally studied as …

[HTML][HTML] The Hippo signalling pathway and its implications in human health and diseases

M Fu, Y Hu, T Lan, KL Guan, T Luo… - Signal transduction and …, 2022 - nature.com
As an evolutionarily conserved signalling network, the Hippo pathway plays a crucial role in
the regulation of numerous biological processes. Thus, substantial efforts have been made …

Clinical development of metal complexes as photosensitizers for photodynamic therapy of cancer

J Karges - Angewandte chemie international edition, 2022 - Wiley Online Library
Cancer has emerged over the last decades as one of the deadliest diseases in the world.
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …

[HTML][HTML] Anticancer drug resistance: An update and perspective

R Nussinov, CJ Tsai, H Jang - Drug Resistance Updates, 2021 - Elsevier
Driver mutations promote initiation and progression of cancer. Pharmacological treatment
can inhibit the action of the mutant protein; however, drug resistance almost invariably …

[HTML][HTML] Drug resistance and combating drug resistance in cancer

X Wang, H Zhang, X Chen - Cancer drug resistance, 2019 - ncbi.nlm.nih.gov
Cancer is the second leading cause of death in the US. Current major treatments for cancer
management include surgery, cytotoxic chemotherapy, targeted therapy, radiation therapy …

[HTML][HTML] Multidrug resistance in cancer: understanding molecular mechanisms, immunoprevention and therapeutic approaches

TB Emran, A Shahriar, AR Mahmud, T Rahman… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the leading causes of death worldwide. Several treatments are available for
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …

[HTML][HTML] Apoptosis deregulation and the development of cancer multi-drug resistance

CM Neophytou, IP Trougakos, N Erin, P Papageorgis - Cancers, 2021 - mdpi.com
Simple Summary Despite recent therapeutic advances against cancer, many patients do not
respond well or respond poorly, to treatment and develop resistance to more than one anti …