[HTML][HTML] Towards a future where Alzheimer's disease pathology is stopped before the onset of dementia

WM van der Flier, ME de Vugt, EMA Smets, M Blom… - Nature aging, 2023 - nature.com
Alzheimer's disease (AD) is a major healthcare challenge with no curative treatment at
present. To address this challenge, we need a paradigm shift, where we focus on pre …

[HTML][HTML] Communication about diagnosis, prognosis, and prevention in the memory clinic: perspectives of European memory clinic professionals

HMA Hendriksen, AM van Gils, AC van Harten… - Alzheimer's Research & …, 2023 - Springer
Background The paradigm shift towards earlier Alzheimer's disease (AD) stages and
personalized medicine creates new challenges for clinician-patient communication. We …

[HTML][HTML] Use of a digital tool to support the diagnostic process in memory clinics–a usability study

AM van Gils, HFM Rhodius-Meester… - Alzheimer's Research & …, 2024 - Springer
Background Both memory clinic professionals and patients see value in digital tools, yet
these hardly find their way to clinical practice. We explored the usability of a digital tool to …

[HTML][HTML] Computerized decision support is an effective approach to select memory clinic patients for amyloid-PET

HFM Rhodius-Meester, IS van Maurik, LE Collij… - Plos one, 2024 - journals.plos.org
Background The use of amyloid-PET in dementia workup is upcoming. At the same time,
amyloid-PET is costly and limitedly available. While the appropriate use criteria (AUC) aim …

The expectations and experiences of patients regarding the diagnostic workup at a specialized memory clinic: An interview study

M Aspö, M Sundell, M Protsiv, F Wiggenraad… - Health …, 2024 - Wiley Online Library
Background Because of the shift towards earlier diagnosis of dementia and/or Alzheimer's
disease (AD), increasing numbers of individuals with subjective cognitive decline (SCD) and …

Predicting Cognitive Decline in Amyloid-Positive Patients With Mild Cognitive Impairment or Mild Dementia

PJ van der Veere, J Hoogland, LNC Visser… - Neurology, 2024 - neurology.org
Background and Objectives Cognitive decline rates in Alzheimer disease (AD) vary greatly.
Disease-modifying treatments may alter cognitive decline trajectories, rendering their …

Searching for the grail: may machine learning be a road to clinical use of brain MRI segmentation?

M Quarantelli - European Radiology, 2024 - Springer
MRI segmentation offers the possibility to assess regional brain atrophy in a quantitative,
operator-independent manner. This approach has shown potential advantages when …

Biomarker disclosure protocols in prodromal Alzheimer's disease clinical trials

A Rahman‐Filipiak, C Bolton, JD Grill… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION The development of biomarkers for Alzheimer's disease (AD) has allowed
researchers to increase sample homogeneity and test candidate treatments earlier in the …

Patient Perspectives on Learning of a Psychosis Diagnosis

T Neaves - 2023 - uhra.herts.ac.uk
Background: The experience of receiving psychiatric diagnoses is under researched. The
impact of how an individual receives a diagnosis of psychosis, as used in early intervention …

[PDF][PDF] Trust & Patient-centeredness

M Raj, M Catlett, S Weinberg, F Jimenez, E Cope… - 2023 - cdsic.ahrq.gov
PURPOSE The Clinical Decision Support Innovation Collaborative (CDSiC) Trust and
Patient-centeredness Workgroup is charged with (1) supporting the design, implementation …