Processing and biomedical applications of novel eco-sustainable fluconazole–loaded zinc oxide (ZnO) encapsulated chitosan (CS) biopolymer nanocomposite by …

A Das, T Ringu, S Ghosh, N Pramanik - Materials Today Communications, 2023 - Elsevier
Drug resistance and a lack of effective antifungal treatments have spurred the research and
development of novel therapeutics to combat the fungus Candida albicans. Candida is …

Fluconazole-loaded TEOS-modified nanocellulose 3D scaffolds–Fabrication, characterization and its application as vaginal drug delivery system

M Ahuja - Journal of Drug Delivery Science and Technology, 2022 - Elsevier
The present research utilizes the nanocellulose extracted from rice or wheat straw and
modified using tetraethyl orthosilicate (TEOS). The 2-factor 3-level central composite …

[HTML][HTML] Stability of α-lactose monohydrate: The discovery of dehydration triggered solid-state epimerization

T Alzoubi, GP Martin, DJ Barlow, PG Royall - International Journal of …, 2021 - Elsevier
Lactose is present as an excipient in nearly half of all solid medicines. Despite the
assumption of chemical stability, in aqueous solution, the chiral composition of lactose is …

Azole and 5-nitroimidazole based nanoformulations are potential antiamoebic drug candidates against brain-eating amoebae

N Akbar, K Hussain, M Khalid, R Siddiqui… - Journal of Applied …, 2023 - academic.oup.com
Aim Herein, the anti-parasitic activity of azoles (fluconazole and itraconazole) and 5-
nitroimdazole (metronidazole) against the brain-eating amoebae: Naegleria fowleri and …

A combined differential scanning calorimetry and thermogravimetry approach for the effective assessment of drug substance-excipient compatibility

B Rojek, M Wesolowski - Journal of Thermal Analysis and Calorimetry, 2023 - Springer
Differential scanning calorimetry (DSC) is a tool particularly recommended for rapid
compatibility screening between active pharmaceutical ingredients (APIs) and excipients …

Nanocellulose-gellan cross-linked scaffolds for vaginal delivery of fluconazole

R Pahwa, M Ahuja - International Journal of Biological Macromolecules, 2023 - Elsevier
The objective of this research is to formulate lyophilized fluconazole-loaded nanocellulose-
gellan scaffolds cross-linked using trisodium trimetaphosphate as a vaginal drug delivery …

Ketoconazole: compatibility with pharmaceutical excipients using DSC and TG techniques

MS Lopes, TA Catelani, ALCS Nascimento… - Journal of Thermal …, 2020 - Springer
Ketoconazole (KTZ) is an antifungal agent responsible for the inhibition of 14-α-demethylase
sterol. The drug–excipient compatibility studies play an important role in pharmaceutical …

Compatibility study of hydroxychloroquine sulfate with pharmaceutical excipients using thermal and nonthermal techniques for the development of hard capsules

ANF Moraes, LAD Silva, MA de Oliveira… - Journal of Thermal …, 2020 - Springer
Hydroxychloroquine is effectively used in the treatment for malaria, lupus erythematosus and
rheumatoid arthritis. The study of drug–excipient compatibility is an important tool for the …

Compatibility study between antiparkinsonian drug Levodopa and excipients by FTIR spectroscopy, X-ray diffraction and thermal analysis

I Ledeti, S Bolintineanu, G Vlase, D Circioban… - Journal of Thermal …, 2017 - Springer
Abstract Levodopa (L-Dopa or LD) is nowadays considered one of the essential medicines
in the World Health Organization list, being a main treatment component for Parkinson's …

Solubility of fluconazole in (ethanol+ water) mixtures: Determination, correlation, dissolution thermodynamics and preferential solvation

S Akay, B Kayan, F Martínez - Journal of Molecular Liquids, 2021 - Elsevier
In this research, the equilibrium mole fraction solubility of fluconazole (FLC) in some
aqueous-ethanolic mixtures was determined at seven temperatures from (293.15 to 323.15) …