Tumor necrosis factor antagonist mechanisms of action: a comprehensive review
D Tracey, L Klareskog, EH Sasso, JG Salfeld… - Pharmacology & …, 2008 - Elsevier
During the past 30 years, elucidation of the pathogenesis of rheumatoid arthritis, Crohn's
disease, psoriasis, psoriatic arthritis and ankylosing spondylitis at the cellular and molecular …
disease, psoriasis, psoriatic arthritis and ankylosing spondylitis at the cellular and molecular …
Angiogenesis and chronic inflammation: cause or consequence?
Evidence has been gathered regarding the association between angiogenesis and
inflammation in pathological situations. These two phenomena have long been coupled …
inflammation in pathological situations. These two phenomena have long been coupled …
PI3k/Akt signalling pathway plays a crucial role in the anti-inflammatory effects of curcumin in LPS-activated microglia
Microglia are resident macrophages in the central nervous system (CNS) deputed to defend
against pathogens. Persistent or acute inflammation of microglia leads to CNS disorders, so …
against pathogens. Persistent or acute inflammation of microglia leads to CNS disorders, so …
The IGF-I signaling pathway
L Laviola, A Natalicchio… - Current pharmaceutical …, 2007 - ingentaconnect.com
The insulin-like growth factor (IGF)-I is implicated in the regulation of protein turnover and
exerts potent mitogenic and differentiating effects on most cell types. IGF-I biological actions …
exerts potent mitogenic and differentiating effects on most cell types. IGF-I biological actions …
Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue
AM Grabiec, S Krausz, W De Jager… - The journal of …, 2010 - journals.aai.org
Macrophages contribute significantly to the pathology of many chronic inflammatory
diseases, including rheumatoid arthritis (RA), asthma, and chronic obstructive pulmonary …
diseases, including rheumatoid arthritis (RA), asthma, and chronic obstructive pulmonary …
Pomegranate extract alleviates disease activity and some blood biomarkers of inflammation and oxidative stress in Rheumatoid Arthritis patients
M Ghavipour, G Sotoudeh, E Tavakoli… - European journal of …, 2017 - nature.com
Results: Compared with the placebo group, POMx supplement significantly reduced the
score of DAS28 (P< 0.001) which could be related to the decrease in swollen (P< 0.001) and …
score of DAS28 (P< 0.001) which could be related to the decrease in swollen (P< 0.001) and …
[HTML][HTML] Marine bioactives: Pharmacological properties and potential applications against inflammatory diseases
N D'Orazio, MA Gammone, E Gemello, M De Girolamo… - Marine drugs, 2012 - mdpi.com
Inflammation is a hot topic in medical research, because it plays a key role in inflammatory
diseases: rheumatoid arthritis (RA) and other forms of arthritis, diabetes, heart diseases …
diseases: rheumatoid arthritis (RA) and other forms of arthritis, diabetes, heart diseases …
[HTML][HTML] Hypoxia enhances chondrogenesis and prevents terminal differentiation through PI3K/Akt/FoxO dependent anti-apoptotic effect
HH Lee, CC Chang, MJ Shieh, JP Wang, YT Chen… - Scientific reports, 2013 - nature.com
Hypoxia, a common environmental condition, influences cell signals and functions. Here, we
compared the effects of hypoxia (1% oxygen) and normoxia (air) on chondrogenic …
compared the effects of hypoxia (1% oxygen) and normoxia (air) on chondrogenic …
Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-κB, p38MAPK and Akt …
K Essafi-Benkhadir, A Refai, I Riahi, S Fattouch… - Biochemical and …, 2012 - Elsevier
Chronic inflammation is a hallmark of several pathologies, such as rheumatoid arthritis,
gastritis, inflammatory bowel disease, atherosclerosis and cancer. A wide range of anti …
gastritis, inflammatory bowel disease, atherosclerosis and cancer. A wide range of anti …
Diosmetin exhibits anti‐proliferative and anti‐inflammatory effects on TNF‐α‐stimulated human rheumatoid arthritis fibroblast‐like synoviocytes through regulating the …
Y Chen, Y Wang, M Liu, B Zhou… - Phytotherapy …, 2020 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by inflammation
and proliferation of synovial tissues. Diosmetin is a bioflavonoid possessing an anti …
and proliferation of synovial tissues. Diosmetin is a bioflavonoid possessing an anti …