[HTML][HTML] Molecular targets of natural compounds with anti-cancer properties

M Kubczak, A Szustka, M Rogalińska - International Journal of Molecular …, 2021 - mdpi.com
Cancer is the second leading cause of death in humans. Despite rapid developments in
diagnostic methods and therapies, metastasis and resistance to administrated drugs are the …

Cancer chemoprevention through dietary antioxidants: progress and promise

N Khan, F Afaq, H Mukhtar - Antioxidants & redox signaling, 2008 - liebertpub.com
It is estimated that nearly one-third of all cancer deaths in the United States could be
prevented through appropriate dietary modification. Various dietary antioxidants have …

Resveratrol: a multitargeted agent for age-associated chronic diseases

KB Harikumar, BB Aggarwal - Cell cycle, 2008 - Taylor & Francis
Extensive research within the last decade has revealed that most chronic illnesses such as
cancer, cardiovascular and pulmonary diseases, neurological diseases, diabetes, and …

Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer

A Malik, F Afaq, S Sarfaraz… - Proceedings of the …, 2005 - National Acad Sciences
Prostate cancer is the most common invasive malignancy and the second leading cause of
cancer-related deaths among US males, with a similar trend in many Western countries. One …

Review of the pharmacological effects of Vitis vinifera (Grape) and its bioactive compounds

M Nassiri‐Asl, H Hosseinzadeh - Phytotherapy Research: An …, 2009 - Wiley Online Library
Vitis vinifera, known as the grapevine, is native to southern Europe and Western Asia. Grape
seed and skin contain several active components including flavonoids, polyphenols …

[HTML][HTML] Transcriptomic and metabolite analyses of Cabernet Sauvignon grape berry development

LG Deluc, J Grimplet, MD Wheatley, RL Tillett… - BMC genomics, 2007 - Springer
Background Grape berry development is a dynamic process that involves a complex series
of molecular genetic and biochemical changes divided into three major phases. During …

The role of estrogens and estrogen receptors in normal prostate growth and disease

GS Prins, KS Korach - Steroids, 2008 - Elsevier
Estrogens have significant direct and indirect effects on prostate gland development and
homeostasis and have been long suspected in playing a role in the etiology of prostatic …

Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein

A Kotha, M Sekharam, L Cilenti, K Siddiquee… - Molecular cancer …, 2006 - AACR
Resveratrol is a naturally occurring phytoalexin with antioxidant and antiinflammatory
properties. Recent studies suggest that resveratrol possesses anticancer effects, although its …

Epigenetic modifications of gene expression by lifestyle and environment

QA Abdul, BP Yu, HY Chung, HA Jung… - Archives of pharmacal …, 2017 - Springer
Epigenetics oftenly described as the heritable changes in gene expression independent of
changes in DNA sequence. Various environmental factors such as nutrition-dietary …

[HTML][HTML] Natural compounds in prostate cancer prevention and treatment: mechanisms of action and molecular targets

F Fontana, M Raimondi, M Marzagalli, A Di Domizio… - Cells, 2020 - mdpi.com
Prostate cancer (PCa) represents a major cause of cancer mortality among men in
developed countries. Patients with recurrent disease initially respond to androgen …