[HTML][HTML] Relationship between ferroptosis and mitophagy in cardiac ischemia reperfusion injury: a mini-review

C Liu, Z Li, B Li, W Liu, S Zhang, K Qiu, W Zhu - PeerJ, 2023 - peerj.com
Cardiovascular diseases (CVD), with high morbidity and mortality, seriously affect people's
life and social development. Clinically, reperfusion therapy is typically used to treat ischemic …

[HTML][HTML] Mitophagy regulation following myocardial infarction

A Turkieh, Y El Masri, F Pinet, E Dubois-Deruy - Cells, 2022 - mdpi.com
Mitophagy, which mediates the selective elimination of dysfunctional mitochondria, is
essential for cardiac homeostasis. Mitophagy is regulated mainly by PTEN-induced putative …

[HTML][HTML] Dl-3-n-butylphthalide attenuates myocardial ischemia reperfusion injury by suppressing oxidative stress and regulating cardiac mitophagy via the PINK1 …

D Zhang, N Zheng, X Fu, J Shi… - Journal of Thoracic …, 2022 - ncbi.nlm.nih.gov
Background Acute myocardial infarction (AMI) is one of the leading causes of mortality
worldwide. Undesirable myocardial damage may occur during reperfusion of the ischemic …

[HTML][HTML] Mitochondrial-targeted therapies require mitophagy to prevent oxidative stress induced by SOD2 inactivation in hypertrophied cardiomyocytes

V Peugnet, M Chwastyniak, P Mulder, S Lancel… - Antioxidants, 2022 - mdpi.com
Heart failure, mostly associated with cardiac hypertrophy, is a major cause of illness and
death. Oxidative stress causes accumulation of reactive oxygen species (ROS), leading to …

The structure and function of FUN14 domain-containing protein 1 and its contribution to cardioprotection by mediating mitophagy

Y Lv, Z Yu, P Zhang, X Zhang, H Li, T Liang… - Frontiers in …, 2024 - frontiersin.org
Cardiovascular disease (CVD) is a serious public health risk, and prevention and treatment
efforts are urgently needed. Effective preventive and therapeutic programs for …

Alpha-lipoic Acid Protects Against Chronic Alcohol Consumption-induced Cardiac Damage by the Aldehyde Dehydrogenase 2–associated PINK/Parkin Pathway

C Shen, X Chen, Y Cao, Y Du, X Xu, Q Wu… - Journal of …, 2023 - journals.lww.com
Chronic alcohol intake contributes to high mortality rates due to ethanol-induced cardiac
hypertrophy and contractile dysfunction, which are accompanied by increased oxidative …

[HTML][HTML] Transcriptomic and Lipidomic Mapping of Macrophages in the Hub of Chronic Beta-Adrenergic-Stimulation Unravels Hypertrophy-, Proliferation-, and Lipid …

S Nadaud, M Flamant, W Le Goff, E Balse, C Pavoine - Biomedicines, 2022 - mdpi.com
Sympathetic nervous system overdrive with chronic release of catecholamines is the most
important neurohormonal mechanism activated to maintain cardiac output in response to …

Overexpression of NAF-1 ameliorates Ischemic Stroke in rats by inhibiting PINK1/Parkin-mediated mitophagy

X Fan, Y Wu, L Deng, T Zuo, S Yang, L Jiang, Q Hu… - 2022 - researchsquare.com
Ischemic stroke (IS) has a high mortality and disability rate worldwide. NAF-1 is involved in
the occurrence and development of nervous system diseases, but its involvement in the …

Alpha-lipoic Acid Protects Against Chronic Alcohol Consumption-induced Cardiac Damage via the ALDH2-associated PINK/Parkin Pathway

C Shen, X Chen, Y Cao, Y Du, X Xu, Q Wu… - Journal of …, 2022 - journals.lww.com
Chronic alcohol intake contributes to high mortality rates due to ethanol-induced cardiac
hypertrophy and contractile dysfunction, which are accompanied by increased oxidative …