Equipping cancer-fighting immune cells with chimeric antigen receptor (CAR) has gained
immense attention for cancer treatment. CAR-engineered T cells (CAR T cells) are the first …

Background Pancreatic cancer, referred to as the “monarch of malignancies,” is a neoplastic
growth mostly arising from the epithelial cells of the pancreatic duct and acinar cells. This …

Natural killer (NK) cells are cytotoxic lymphocytes that are critical for the innate immune
system. Engineering NK cells with chimeric antigen receptors (CARs) allows CAR-NK cells …

Natural killer (NK) cells are predominant innate lymphocytes that initiate the early immune
response during infection. NK cells undergo a metabolic switch to fuel augmented …

CD155, also known as the poliovirus receptor, is an adhesion molecule often overexpressed
in tumors of different origins where it promotes cell migration and proliferation. In addition to …

Reinvigorating the killing function of tumor-infiltrating immune cells through the targeting of
regulatory molecules expressed on lymphocytes has markedly improved the prognosis of …

Allogeneic cell therapies, such as those involving macrophages or Natural Killer (NK) cells,
are of increasing interest for cancer immunotherapy. However, the current techniques for …

Immune cell therapy as a revolutionary treatment modality, significantly transformed cancer
care. It is a specialized form of immunotherapy that utilizes living immune cells as …

Immunotherapy has rapidly evolved in the past decades in the battle against cancer.
Chimeric antigen receptor (CAR)-engineered T cells have demonstrated significant success …

Natural killer (NK) cells are cytotoxic innate lymphoid cells that participate in anti-tumour and
anti-viral immune responses. Their ability to rapidly destroy abnormal cells and to enhance …