Recently, click chemistry has provided important advances in biomedical research fields.
Particularly, copper-free click chemistry including strain-promoted azide–alkyne …

As one typical intratumoral nanosynthetic medicine (INSM), in situ biosynthesized
supramolecular self-assemblies point at the accurate transformation of disordered small …

Passive targeting of large nanoparticles by the enhanced permeability and retention (EPR)
effect is a crucial concept for solid tumor targeting in cancer nanomedicine. There is …

The completion of surgical resection is a key prognostic factor in brain tumor treatment. This
requires surgeons to identify residual tumors in theater as well as to margin the proximity of …

Near-infrared (NIR) fluorescent probes are among the most attractive chemical tools for
biomedical imaging. However, their in vivo applications are hindered by albumin binding …

This is the first report on the development of a covalently bone morphogenetic protein-2
(BMP2)-immobilized hydrogel that is suitable for osteogenic differentiation of human …

The physicochemical properties of nanomaterials play a key role in tissue‐specific targeting
by reducing nonspecific background uptake as well as controlling biodistribution and …

The development of advanced bioorthogonal reactions for detection and labeling of
biomolecules is significant in chemical biology. Recently, researchers have found that …

The global burden of bone-related diseases is increasing in the aging society; thus,
improved bone targeted imaging for their early identification and treatment are needed. In …

The physicochemical properties of nanomaterials play a key role in tissue-specific targeting
by reducing nonspecific background uptake as well as controlling biodistribution and …