Aspartyl peptidase May1 induces host inflammatory response by altering cell wall composition in the fungal pathogen Cryptococcus neoformans

Y Li, B Chadwick, T Pham, X Xie, X Lin - Mbio, 2024 - Am Soc Microbiol
Cryptococcus neoformans causes cryptococcal meningoencephalitis, a disease that kills
more than 180,000 people annually. Contributing to its success as a fungal pathogen is its …

Illuminating the Cryptococcus neoformans species complex: unveiling intracellular structures with fluorescent-protein-based markers

R Shi, X Lin - Genetics, 2024 - academic.oup.com
Cryptococcus neoformans is a fungal pathogen of the top critical priority recognized by the
World Health Organization. This clinically important fungus also serves as a eukaryotic …

Immunological correlates of protection mediated by a whole organism, Cryptococcus neoformans, vaccine deficient in chitosan

CA Specht, R Wang, LVN Oliveira, MM Hester… - Mbio, 2024 - journals.asm.org
The global burden of infections due to the pathogenic fungus Cryptococcus is substantial in
persons with low CD4+ T-cell counts. Previously, we deleted three chitin deacetylase genes …

[HTML][HTML] Protection against experimental cryptococcosis elicited by Cationic Adjuvant Formulation 01-adjuvanted subunit vaccines

R Wang, LVN Oliveira, MM Hester, D Carlson… - bioRxiv, 2024 - ncbi.nlm.nih.gov
The fungal infection, cryptococcosis, is responsible for> 100,000 deaths annually. No
licensed vaccines are available. We explored the efficacy and immune responses of subunit …

[图书][B] Deciphering the Function of HAM1 in the Biology of Cryptococcus neoformans

EA Yee - 2023 - search.proquest.com
Cryptococcus neoformans is a global fungal pathogen that primarily impacts
immunocompromised individuals. Responsible for~ 200,000 yearly cases in the HIV+ …

Deciphering the Function of HAM1 in the Biology of Cryptococcus neoformans Item

E Arsenault Yee - 2023 - curate.nd.edu
Cryptococcus neoformans is a global fungal pathogen that primarily impacts
immunocompromised individuals. Responsible for~ 200,000 yearly cases in the HIV+ …

CD4+ T細胞非依存性クリプトコックス症ワクチン真菌特異的記憶CD8+ T細胞を誘導するためには何が必要か?

上野圭吾, 永森晶子, 本弓奈穂子, 宮﨑義継 - 日本医真菌学会雑誌, 2024 - jstage.jst.go.jp
抄録 病原性真菌 Cryptococcus neoformans や Cryptococcus gattii は, 一般的に肺を侵入門戸
として感染しクリプトコックス症を引き起こす. 中枢神経系に播種する病態では重篤になる症例も多く …