Effect of cell–cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells
Heterotypic cell interaction between parenchymal cells and nonparenchymal neighbors has
been reported to modulate cell growth, migration, and/or differentiation. In both the …
been reported to modulate cell growth, migration, and/or differentiation. In both the …
Gap junctions as targets for cancer chemoprevention and chemotherapy
JE Trosko, RJ Ruch - Current Drug Targets, 2002 - ingentaconnect.com
The development of the most efficacious strategy for the prevention and treatment of cancers
is based on understanding the underlying mechanisms of carcinogenesis. This includes the …
is based on understanding the underlying mechanisms of carcinogenesis. This includes the …
Connexin 43 hemichannels mediate Ca2+‐regulated transmembrane NAD+ fluxes in intact cells
S Bruzzone, L Guida, E Zocchi, L Franco… - The FASEB …, 2001 - Wiley Online Library
ABSTRACT A previously unrecognized passive transport for pyridine dinucleotides has
been described recently in the plasmamembrane of several mammalian cells. Despite …
been described recently in the plasmamembrane of several mammalian cells. Despite …
Microfabrication of hepatocyte/fibroblast co‐cultures: Role of homotypic cell interactions
Cell− cell interactions are important in embryogenesis, in adult physiology and
pathophysiology of many disease processes. Co‐cultivation of parenchymal and …
pathophysiology of many disease processes. Co‐cultivation of parenchymal and …
[HTML][HTML] Mechanism of Ca2+-Dependent Pro-Apoptotic Action of Selenium Nanoparticles, Mediated by Activation of Cx43 Hemichannels
EA Turovsky, EG Varlamova - Biology, 2021 - mdpi.com
Simple Summary The development of new methods of anticancer therapy is an urgent task
of modern biology. The use of selenium and its compounds as anticancer drugs have …
of modern biology. The use of selenium and its compounds as anticancer drugs have …
Probing heterotypic cell interactions: hepatocyte function in microfabricated co-cultures
Replacement of liver function using extracorporeal bioartificial systems has been attempted
with limited success. The instability of the hepatocyte phenotype in vitro has restricted the …
with limited success. The instability of the hepatocyte phenotype in vitro has restricted the …
Connexin 43 (cx43) enhances chemotherapy‐induced apoptosis in human glioblastoma cells
RP Huang, MZ Hossain, R Huang… - … journal of cancer, 2001 - Wiley Online Library
Stable re‐expression of connexin 43 (cx43) in human glioblastoma suppresses
transformation and tumorigenicity. The present study was designed to examine the role of …
transformation and tumorigenicity. The present study was designed to examine the role of …
Effect of cell density on osteoblastic differentiation and matrix degradation of biomimetic dense collagen scaffolds
M Bitar, RA Brown, V Salih, AG Kidane… - …, 2008 - ACS Publications
Plastic compression of hyperhydrated collagen gels produces tissue-like scaffolds of
enhanced biomechanical properties. By increasing collagen density, these scaffolds could …
enhanced biomechanical properties. By increasing collagen density, these scaffolds could …
Suppression of human prostate cancer cell growth by forced expression of connexin genes
PP Mehta, C Perez‐Stable, M Nadji… - Developmental …, 1999 - Wiley Online Library
The cell‐to‐cell channels in gap junctions, formed of proteins called connexins (Cxs),
provide a direct intercellular pathway for the passage of small signaling molecules (≤ 1 kD) …
provide a direct intercellular pathway for the passage of small signaling molecules (≤ 1 kD) …
[PDF][PDF] Gap junctions in the ovaries
AT Grazul-Bilska, LP Reynolds, DA Redmer - Biology of reproduction, 1997 - Citeseer
The mammalian gap junction is a cellular structure between adjacent cells, wherein the
apposed cellular membranes are separated by an apparent gap of approximately 3 nm (Fig …
apposed cellular membranes are separated by an apparent gap of approximately 3 nm (Fig …