Gap-junction communication in chemical carcinogenesis
RJ Ruch, JE Trosko - Drug metabolism reviews, 2001 - Taylor & Francis
In a recent review article,“Risk Assessment for Possible Carcinogens: A Critical Look”(1), Dr.
Emmanuel Farber states,“There is a developing speculation that agents or circumstances …
Emmanuel Farber states,“There is a developing speculation that agents or circumstances …
Role of gap junctions in lung neoplasia
RJ Ruch, K Cesen-Cummings… - Experimental lung …, 1998 - Taylor & Francis
Reduced gap junctional intercellular communication (GJIC) has been noted in many types of
neoplastic cells and may contribute to the neoplastic phenotype. This study assessed GJIC …
neoplastic cells and may contribute to the neoplastic phenotype. This study assessed GJIC …
Effective asymmetry in gap junctional intercellular communication between populations of human normal lung fibroblasts and lung carcinoma cells
ZQ Zhang, Y Hu, BJ Wang, ZX Lin, CCG Naus… - …, 2004 - academic.oup.com
The dysfunction of homologous and/or heterologous gap junctional intercellular
communication (GJIC) has been implicated in tumorigenesis of many kinds of cells. Here we …
communication (GJIC) has been implicated in tumorigenesis of many kinds of cells. Here we …
Neoplastic phenotype of gap‐junctional intercellular communication–deficient WB rat liver epithelial cells and its reversal by forced expression of connexin 32
RS Rae, PP Mehta, CC Chang… - … in cooperation with …, 1998 - Wiley Online Library
Gap‐junctional intercellular communication (GJIC) is involved in cellular growth control and
is often reduced in neoplastic cells. In this study, four GJIC‐deficient rat liver epithelial cell …
is often reduced in neoplastic cells. In this study, four GJIC‐deficient rat liver epithelial cell …
Oxidative stress, signal transduction, and intercellular communication in radiation carcinogenesis
JE Trosko, T Inoue - Stem Cells, 1997 - Wiley Online Library
During the evolution of multicellular organisms, survival in an aerobic environment came
about by adaptive responses, both to the endogenous oxidative metabolism within the cells …
about by adaptive responses, both to the endogenous oxidative metabolism within the cells …
ACCELERATED PAPER: Inhibition of gap junctional intercellular communication by barbiturates in long-term primary cultured rat hepatocytes is correlated with liver …
P Ren, RJ Ruch - Carcinogenesis, 1996 - academic.oup.com
Rodent liver tumor formation can be promoted by certain barbiturates and this may involve
their ability to inhibit hepatocyte gap junctional intercellular communication (GJIC). In order …
their ability to inhibit hepatocyte gap junctional intercellular communication (GJIC). In order …
Restored gap junctional communication in non-tumorigenic HeLa-normal human fibroblast hybrids.
HL de Feijter-Rupp, T Hayashi, GH Kalimi… - …, 1998 - academic.oup.com
Gap junctional intercellular communication (GJIC) has been implicated in homeostasis,
development, differentiation, wound healing or regeneration and adaptive responses of …
development, differentiation, wound healing or regeneration and adaptive responses of …
Pathological significance of connexin 26 expression in colorectal adenocarcinoma
R Hong, SC Lim - Oncology reports, 2008 - spandidos-publications.com
This study was conducted to determine the level of expression and cellular localization of
connexin 26 (Cx26) and the expression of p53 in colorectal adenocarcinoma as well as their …
connexin 26 (Cx26) and the expression of p53 in colorectal adenocarcinoma as well as their …
Impaired wound healing compositions and treatments
US8063023B2 - Impaired wound healing compositions and treatments - Google Patents
US8063023B2 - Impaired wound healing compositions and treatments - Google Patents …
US8063023B2 - Impaired wound healing compositions and treatments - Google Patents …
Role of gap junctions in cellular growth control and neoplasia: Evidence and mechanisms
RJ Ruch - Current topics in membranes, 1999 - Elsevier
Publisher Summary This chapter focuses on the role of gap junctional intercellular
communication (GJIC) in cellular growth control and neoplasia and considers the large body …
communication (GJIC) in cellular growth control and neoplasia and considers the large body …