Intrathecal pseudodelivery of drugs is a novel route to administer medications to treat
neurodegenerative diseases based on the CSF-sink therapeutic strategy by means of …

Membrane proteins determine the precise function of each membrane and, therefore, the
function of each cell type. These proteins essential roles in cell physiology, participating in …

The clinical application of conventional medications for hepatocellular carcinoma treatment
has been severely restricted by their adverse effects and unsatisfactory therapeutic …

The aim of the present study was to examine the association between miRNA levels in
extracellular vesicles (EVs) from serum and the severity of Major Depression (MD). Patient …

Targeted delivery of pharmacologically active molecules, metabolites, and growth factors to
the brain parenchyma has become one of the major challenges following the onset of …

The limitations of conventional therapeutic treatments prevailed in the development of
nanotechnology-based medical formulations, termed nanomedicine. Nanomedicine is an …

Posterior ocular disease, a disease that accounts for 55% of all ocular diseases, can
contribute to permanent vision loss if left without treatment. Due to the special structure of the …

The prognosis of peripheral nerve injury (PNI) is usually poor, and currently, there is no
effective treatment for PNI. Studies have shown that exosomes derived from mesenchymal …

Stimuli-responsive supramolecular polymers are ordered nanosized materials that are held
together by non-covalent interactions (hydrogen-bonding, metal-ligand coordination, π …

Exosomes are tiny vesicles delivered by specialized cells that carry RNA, lipids, and
proteins. The distinctive potential of exosomes in intercellular communication and their …