While critically ill patients experience a life-threatening illness, they commonly contract
ventilator-associated pneumonia. This nosocomial infection increases morbidity and likely …

The mutant selection window is an antimicrobial concentration range extending from the
minimal concentration required to block the growth of wild-type bacteria up to that required …

Although the fluoroquinolones are presently used to treat tuberculosis primarily in cases
involving resistance or intolerance to first-line antituberculosis therapy, these drugs are …

Post-traumatic endophthalmitis is an uncommon yet devastating complication of an open
globe injury. Risk factors include presence of an intraocular foreign body (IOFB), lens …

The recent surge in multidrug-resistant pathogens combined with the diminishing antibiotic
pipeline has created a growing need to optimize the use of our existing antibiotic …

OBJECTIVE: To evaluate the early bactericidal activity (EBA) of the new fluoroquinolones
levofloxacin, gatifloxacin and moxifloxacin in patients with pulmonary tuberculosis (PTB) …

Therapy of ventilator-associated pneumonia should be a patient-based approach focusing
on some key features are listed here: early initial therapy should be based on broad …

Ventilator-associated pneumonia is the most frequent intensive care unit (ICU)-related
infection in patients requiring mechanical ventilation. In contrast to other ICU-related …

The connection between regional rates of antimicrobial resistance in Streptococcus
pneumoniae and regional antimicrobial use in Finland was investigated. During the 6-year …

The continuing escalation of antimicrobial resistant human pathogens and the limited
number of new antimicrobial agents under development has dictated that our knowledge on …