Background Nicotine replacement therapy (NRT) aims to replace nicotine from cigarettes to
ease the transition from cigarette smoking to abstinence. It works by reducing the intensity of …

Tobacco use, especially cigarette smoking, is a major risk factor for cardiovascular morbidity
and mortality and is the leading preventable cause of death worldwide. Comprehensive …

Background Nicotine replacement therapy (NRT) aims to temporarily replace much of the
nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms …

Background As summarised in the most recent Cochrane review, the few clinical trials on e-
cigarettes are largely focused on smoking cessation. We aimed to determine the naturalistic …

Combustible tobacco use remains the number one preventable cause of disease, disability,
and death in the United States. Electronic nicotine delivery systems (ENDS), which include e …

Importance Genome-wide hypothesis-free discovery methods have identified loci that are
associated with heavy smoking in adulthood. Research is needed to understand …

The W orld H ealth O rganization estimates that 1 billion people will die from tobacco‐related
illnesses this century. Most health‐care providers, however, fail to treat tobacco …

Smoking cessation is crucial for reducing cancer risk and premature mortality. The US
Preventive Services Task Force (USPSTF) has recommended annual lung cancer screening …

Background Cigarette smoking is one of the leading causes of early death. Varenicline
[Champix (UK), Pfizer Europe MA EEIG, Brussels, Belgium; or Chantix (USA), Pfizer Inc …

Background: Most studies of electronic nicotine delivery systems (ENDS) compare self-
selected users versus nonusers. The few randomized studies to date generally support a …