Background & Aims Celiac disease is a major public health problem worldwide. Although
initially it was reported from countries with predominant Caucasian populations, it now has …

Current knowledge is insufficient to explain why only a proportion of individuals exposed to
environmental carcinogens or carrying a genetic predisposition to cancer develop disease …

Helicobacter pylori is highly adapted for colonization of the human stomach and is present in
about half of the human population. When present, H pylori is usually the numerically …

Objective An international meeting was organised to develop consensus on (1) the
landmarks to define the gastro-oesophageal junction (GOJ),(2) the occurrence and …

Background & Aims Central adiposity has been implicated as a risk factor for Barrett's
esophagus (BE) and esophageal adenocarcinoma (EAC), possibly promoting the …

Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease but the
second cause of death among NAFLD patients are attributed to malignancies at both …

Adipose tissue is a highly dynamic endocrine tissue and constitutes a central node in the
interorgan crosstalk network through adipokines, which cause pleiotropic effects, including …

Although scientific knowledge in viral oncology has exploded in the 20th century, the role of
bacteria as mediators of oncogenesis has been less well elucidated. Understanding …

Background & Aims Infection with Helicobacter pylori, particularly the cytotoxin-associated
gene A (cagA)+ strain, is believed to protect against Barrett's esophagus, but it is not clear if …

Obesity is a complex disease caused by the interaction of a myriad of genetic, dietary,
lifestyle and environmental factors, which favors a chronic positive energy balance, leading …