The neutrophil is an essential component of the innate immune system, and its function is
vital to human life. Its production increases in response to virtually all forms of inflammation …

OBJECTIVE: This population-based, prospective, cohort study was designed to determine
the population incidence and outcomes of pediatric acute lung injury. METHODS: Between …

Deliberate induction of prophylactic hypercapnic acidosis protects against lung injury after in
vivo ischemia–reperfusion and ventilation-induced lung injury. However, the efficacy of …

Critical care medicine developed out of other subspecialties' need to provide care for their
most critically ill patients. Advanced technologies, the understanding of the pathophysiology …

Objectives: To describe the changes that have occurred in mechanical ventilation in children
with acute lung injury in our institution over the last 10–15 yrs and to examine the impact of …

Objective: To investigate whether acute hypercapnic acidosis—induced by adding CO 2 to
inspired gas—would protect against severe systemic sepsis-induced lung and systemic …

Objective: Deliberate induction of hypercapnic acidosis protects against lung injury after
nonseptic lung injury. In contrast, concerns exist regarding the effects of hypercapnic …

Acute hypoxemic respiratory failure (AHRF) is one of the hallmarks of acute lung injury (ALI)
and acute respiratory distress syndrome (ARDS), which are caused by an inflammatory …

Background Hypercapnic acidosis protects against lung injury after ischemia-reperfusion,
endotoxin-induced and ventilation-induced lung injury. The effects of hypercapnic acidosis …

Background Acute hypercapnic acidosis protects against lung injury caused by nonseptic
insults and after both pulmonary and systemic sepsis. The authors wished to dissect the …