Horizontal gene transfer of antibiotic resistance genes in biofilms

C Michaelis, E Grohmann - Antibiotics, 2023 - mdpi.com
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …

Colistin: From the shadows to a One Health approach for addressing antimicrobial resistance

M Rhouma, JY Madec, R Laxminarayan - International Journal of …, 2023 - Elsevier
Antimicrobial resistance (AMR) poses a serious threat to human, animal and environmental
health worldwide. Colistin has regained importance as a last-resort treatment against multi …

ESKAPE and beyond: the burden of coinfections in the COVID-19 pandemic

MÁ Loyola-Cruz, LU Gonzalez-Avila, A Martínez-Trejo… - Pathogens, 2023 - mdpi.com
The ESKAPE group constitute a threat to public health, since these microorganisms are
associated with severe infections in hospitals and have a direct relationship with high …

[HTML][HTML] Colistin resistance and management of drug resistant infections

J Sharma, D Sharma, A Singh, K Sunita - Canadian Journal of …, 2022 - hindawi.com
Colistin resistance is a globalized sensible issue because it has been considered a drug of
the last-line resort to treat drug-resistant bacterial infections. The product of the mobilized …

High prevalence of mgrB-mediated colistin resistance among carbapenem-resistant Klebsiella pneumoniae is associated with biofilm formation, and can be …

AMS Shein, DL Wannigama, PG Higgins, C Hurst… - Scientific Reports, 2022 - nature.com
The global prevalence of colistin-resistant Klebsiella pneumoniae (ColRkp) facilitated by
chromosomal and plasmid-mediated Ara4N or PEtN-remodeled LPS alterations has steadily …

International manufacturing and trade in colistin, its implications in colistin resistance and One Health global policies: A microbiological, economic, and …

M Umair, B Hassan, R Farzana, Q Ali, K Sands… - The Lancet …, 2023 - thelancet.com
Background The emergence of colistin-resistant Enterobacterales is a global public health
concern, yet colistin is still widely used in animals that are used for food as treatment …

Colistin use in european livestock: Veterinary field data on trends and perspectives for further reduction

W Jansen, J van Hout, J Wiegel, D Iatridou… - Veterinary …, 2022 - mdpi.com
Simple Summary The antibiotic colistin has been used for Gram-negative bacterial infections
in veterinary medicine since the 1950s, with resistance rates remaining low. However, due …

Mobile Colistin Resistance (mcr) Gene-Containing Organisms in Poultry Sector in Low- and Middle-Income Countries: Epidemiology, Characteristics, and One Health …

MU Anyanwu, IF Jaja, COR Okpala, EO Njoga… - Antibiotics, 2023 - mdpi.com
Mobile colistin resistance (mcr) genes (mcr-1 to mcr-10) are plasmid-encoded genes that
threaten the clinical utility of colistin (COL), one of the highest-priority critically important …

Colistin resistance mechanisms in Gram-negative bacteria: a Focus on Escherichia coli

M Abavisani, N Bostanghadiri… - Letters in Applied …, 2023 - academic.oup.com
Multidrug-resistant (MDR) Escherichia coli strains have rapidly increased worldwide, and
effective antibiotic therapeutic options are becoming more restricted. As a polymyxin …

Genomic Analysis of ESBL-Producing E. coli in Wildlife from North-Eastern Germany

T Homeier-Bachmann, AK Schütz, S Dreyer, J Glanz… - Antibiotics, 2022 - mdpi.com
Antimicrobial resistance (AMR) is a serious global health threat and extended-spectrum beta-
lactamase (ESBL)-producing Enterobacterales are a major contributor. This study aimed to …