Traumatic Brain Injury (TBI) remains a significant global health challenge, lacking effective
pharmacological treatments. This shortcoming is attributed to TBI's heterogeneous and …

Hederagenin (HG) is a natural pentacyclic triterpenoid that can be isolated from various
medicinal herbs. By modifying the structure of HG, multiple derivatives with superior …

The effects of lycopene (LP) on macrophage immune responses were evaluated in this
study. Compared with the control treatment, LP treatment significantly increased cell vitality …

Objective Ferroptosis is implicated in the pathogenesis of neurodegenerative disorders such
as Alzheimer's disease, Parkinson's disease, and vascular dementia, implying that it may …

Recent genome-wide association studies (GWASs) of several individual sleep traits have
identified hundreds of genetic loci, suggesting diverse mechanisms. Moreover, sleep traits …

The endoplasmic reticulum, a key cellular organelle, regulates a wide variety of cellular
activities. Endoplasmic reticulum autophagy, one of the quality control systems of the …

Neuroinflammation associated with microglial activation plays a role in the development of
Parkinson's disease (PD). The upregulation of interferon regulatory factor 8 (IRF8) in …

Objectives To evaluate the role of hypothermia in the injury of PC12 cells which induced by
OGD/R. To investigate the mechanism of hypothermia intervention to alleviate OGD/R …