The gut microbiome and hypertension

JA O'Donnell, T Zheng, G Meric… - Nature Reviews …, 2023 - nature.com
A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …

Insights into salt handling and blood pressure

DH Ellison, P Welling - New England Journal of Medicine, 2021 - Mass Medical Soc
Salt Handling and Blood Pressure Salt intake is associated with blood pressure, but the
relationship is complex. This review highlights the interplay among renal salt transport, salt …

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of …

G Mancia, R Kreutz, M Brunström, M Burnier… - Journal of …, 2023 - journals.lww.com
Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

Systemic inflammation markers and the prevalence of hypertension: A NHANES cross-sectional study

JP Xu, RX Zeng, YZ Zhang, SS Lin, JW Tan… - Hypertension …, 2023 - nature.com
Systemic inflammation markers have been highlighted recently as related to cardiac and
non-cardiac disorders. However, few studies have estimated pre-diagnostic associations …

Meningeal interleukin-17-producing T cells mediate cognitive impairment in a mouse model of salt-sensitive hypertension

MM Santisteban, S Schaeffer, A Anfray, G Faraco… - Nature …, 2024 - nature.com
Hypertension (HTN), a disease afflicting over one billion individuals worldwide, is a leading
cause of cognitive impairment, the mechanisms of which remain poorly understood. In the …

Signaling pathways in vascular function and hypertension: molecular mechanisms and therapeutic interventions

J Ma, Y Li, X Yang, K Liu, X Zhang, X Zuo… - Signal transduction and …, 2023 - nature.com
Hypertension is a global public health issue and the leading cause of premature death in
humans. Despite more than a century of research, hypertension remains difficult to cure due …

Mosaic theory revised: inflammation and salt play central roles in arterial hypertension

FE Hengel, JP Benitah, UO Wenzel - Cellular & molecular immunology, 2022 - nature.com
The mosaic theory of hypertension was advocated by Irvine Page~ 80 years ago and
suggested that hypertension resulted from the close interactions of different causes …

Endothelial and vascular smooth muscle dysfunction in hypertension

MG de Oliveira, W Nadruz Jr, FZ Monica - Biochemical pharmacology, 2022 - Elsevier
The development of essential hypertension involves several factors. Vascular dysfunction,
characterized by endothelial dysfunction, low-grade inflammation and structural remodeling …

[PDF][PDF] 2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of …

M Brunström, M Burnier… - Journal of …, 2023 - docred-strapi-cms-prod.s3.sa-east-1 …
Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

The Na+/H+ Exchanger 3 in the Intestines and the Proximal Tubule of the Kidney: Localization, Physiological Function, and Key Roles in Angiotensin II-Induced …

SM Nwia, XC Li, APO Leite, R Hassan… - Frontiers in …, 2022 - frontiersin.org
The sodium (Na+)/hydrogen (H+) exchanger 3 (NHE3) is one of the most important Na+/H+
antiporters in the small intestines of the gastrointestinal tract and the proximal tubules of the …