Mobile genetic elements associated with antimicrobial resistance

SR Partridge, SM Kwong, N Firth… - Clinical microbiology …, 2018 - Am Soc Microbiol
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

[HTML][HTML] Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

Integrons: past, present, and future

MR Gillings - Microbiology and molecular biology reviews, 2014 - Am Soc Microbiol
Integrons are versatile gene acquisition systems commonly found in bacterial genomes.
They are ancient elements that are a hot spot for genomic complexity, generating phenotypic …

[HTML][HTML] Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside

MF Lin, CY Lan - World Journal of Clinical Cases: WJCC, 2014 - ncbi.nlm.nih.gov
Acinetobacter baumannii (A. baumannii) is undoubtedly one of the most successful
pathogens in the modern healthcare system. With invasive procedures, antibiotic use and …

[HTML][HTML] Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies of Acinetobacter baumannii

CO Vrancianu, I Gheorghe, IB Czobor, MC Chifiriuc - Microorganisms, 2020 - mdpi.com
Antibiotic resistance is one of the biggest challenges for the clinical sector and industry,
environment and societal development. One of the most important pathogens responsible …

Gene flow, mobile genetic elements and the recruitment of antibiotic resistance genes into Gram-negative pathogens

HW Stokes, MR Gillings - FEMS microbiology reviews, 2011 - academic.oup.com
Antibiotics were one of the great discoveries of the 20th century. However, resistance
appeared even in the earliest years of the antibiotic era. Antibiotic resistance continues to …

Integrons

G Cambray, AM Guerout, D Mazel - Annual review of genetics, 2010 - annualreviews.org
Integrons are genetic elements able to acquire and rearrange open reading frames (ORFs)
embedded in gene cassette units and convert them to functional genes by ensuring their …

[HTML][HTML] The Acinetobacter baumannii Oxymoron: Commensal Hospital Dweller Turned Pan-Drug-Resistant Menace

I Roca, P Espinal, X Vila-Farrés, J Vila - Frontiers in microbiology, 2012 - frontiersin.org
During the past few decades Acinetobacter baumannii has evolved from being a commensal
dweller of health-care facilities to constitute one of the most annoying pathogens …

[HTML][HTML] Integron involvement in environmental spread of antibiotic resistance

T Stalder, O Barraud, M Casellas, C Dagot… - Frontiers in …, 2012 - frontiersin.org
The spread of antibiotic-resistant bacteria is a growing problem and a public health issue. In
recent decades, various genetic mechanisms involved in the spread of resistance genes …

The integron: adaptation on demand

JA Escudero, C Loot, A Nivina, D Mazel - Microbiology spectrum, 2015 - Am Soc Microbiol
The integron is a powerful system which, by capturing, stockpiling, and rearranging new
functions carried by gene encoding cassettes, confers upon bacteria a rapid adaptation …