Long-lasting reflexive and nonreflexive pain responses in two mouse models of fibromyalgia-like condition

B Álvarez-Pérez, M Deulofeu, J Homs, M Merlos… - Scientific reports, 2022 - nature.com
Nociplastic pain arises from altered nociception despite no clear evidence of tissue or
somatosensory system damage, and fibromyalgia syndrome can be highlighted as a …

[HTML][HTML] Increased nociceptive behaviors and spinal c-Fos expression in the formalin test in a rat repeated cold stress model

T Nasu, R Kainuma, H Ota, K Mizumura… - Neuroscience …, 2024 - Elsevier
Repeated cold stress (RCS) can trigger the development of fibromyalgia (FM)-like
symptoms, including persistent deep-tissue pain, although nociceptive changes to the skin …

Long-lasting nociplastic pain modulation by repeated administration of sigma-1 receptor antagonist BD1063 in fibromyalgia-like mouse models

B Álvarez-Pérez, A Bagó-Mas, M Deulofeu… - International Journal of …, 2022 - mdpi.com
Sigma-1 receptor (σ1R) ligands have been shown to be effective at relieving neuropathic
and inflammatory pain, but have not yet been tested in experimental models of fibromyalgia …

Targeting α7-nAChR by galantamine mitigates reserpine-induced fibromyalgia-like symptoms in rats: involvement of cAMP/PKA, PI3K/AKT, and M1/M2 microglia …

AA Atta, WW Ibrahim, AF Mohamed… - European Journal of …, 2023 - Elsevier
Fibromyalgia (FM) is a pain disorder marked by generalized musculoskeletal pain
accompanied by depression, fatigue, and sleep disturbances. Galantamine (Gal) is a …

Knowledge mapping of acupuncture for fibromyalgia from 1990 to 2022: a bibliometric analysis

P Li, H Zheng, Y Chen, Z Liu, J He - Journal of Pain Research, 2022 - Taylor & Francis
Background Fibromyalgia is a rheumatic disease with no specific laboratory markers and is
insensitive to hormonal drugs and nonsteroidal anti-inflammatory drugs commonly used to …

Association between Cardiac Atrioventricular Conduction and Antibodies to Chlamydia Pneumoniae in Fibromyalgia Patients

BK Puri, G Tuckey, L Cowans, GS Lee… - Recent Advances in …, 2023 - ingentaconnect.com
Background: Fibromyalgia patients may complain of cardiovascular symptoms, including
chest pain and palpitations. It has been proposed that infection by Chlamydia pneumoniae …

社会的敗北ストレスモデルラットでは侵害刺激に対する脊髄後角表層ニューロンの興奮性が増大する

井上創太, 太田大樹, 田口徹 - 基礎理学療法学, 2022 - jstage.jst.go.jp
抄録 社会的敗北ストレス (以下, SDS) は痛覚過敏を惹起するが, その病態機構は未解明である.
本研究では, SDS 誘発性疼痛の脊髄機構の解明を試みた. SDS 誘発性疼痛モデルは, Sprague …

[PDF][PDF] 応用薬理学研究室

久米利明, 安東嗣修, 歌大介 - 2019 - toyama.repo.nii.ac.jp
◆ 原 著 1) Izumi Y, Kataoka H, Inose Y, Akaike A, Koyama Y, Kume T. Neuroprotective effect
of an Nrf2-ARE activator identified from a chemical library on dopaminergic neurons. Eur J …