ROS: basic concepts, sources, cellular signaling, and its implications in aging pathways
AJPO de Almeida, JCPL de Oliveira… - Oxidative medicine …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …
molecules with oxidizing properties known as ROS. Despite those molecules being implied …
[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis
MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …
Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian …
Objective To map the diverse health outcomes associated with serum uric acid (SUA) levels.
Design Umbrella review. Data sources Medline, Embase, Cochrane Database of Systematic …
Design Umbrella review. Data sources Medline, Embase, Cochrane Database of Systematic …
[HTML][HTML] Antioxidant effects and mechanism of silymarin in oxidative stress induced cardiovascular diseases
Cardiovascular diseases (CVDs) are considered as the major reason for mortality and
morbidity worldwide. Substantial evidence suggests that increased oxidative stress plays a …
morbidity worldwide. Substantial evidence suggests that increased oxidative stress plays a …
The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion
K Raedschelders, DM Ansley, DDY Chen - Pharmacology & therapeutics, 2012 - Elsevier
Myocardial ischemia-reperfusion injury is an important cause of impaired heart function in
the early postoperative period subsequent to cardiac surgery. Reactive oxygen species …
the early postoperative period subsequent to cardiac surgery. Reactive oxygen species …
Vascular endothelium dysfunction: a conservative target in metabolic disorders
S Jamwal, S Sharma - Inflammation Research, 2018 - Springer
Aim Vascular endothelium plays a role in capillary transport of nutrients and drugs and
regulates angiogenesis, homeostasis, as well as vascular tone and permeability as a major …
regulates angiogenesis, homeostasis, as well as vascular tone and permeability as a major …
[HTML][HTML] Dairy fat and risk of cardiovascular disease in 3 cohorts of US adults
Background: Few prospective studies have examined dairy fat in relation to cardiovascular
disease (CVD) Objective: We aimed to evaluate the association between dairy fat and …
disease (CVD) Objective: We aimed to evaluate the association between dairy fat and …
[HTML][HTML] The relationships among hyperuricemia, endothelial dysfunction, and cardiovascular diseases: molecular mechanisms and clinical implications
P Puddu, GM Puddu, E Cravero, L Vizioli, A Muscari - Journal of cardiology, 2012 - Elsevier
Uric acid is the end product of purine metabolism. Its immediate precursor, xanthine, is
converted to uric acid by an enzymatic reaction involving xanthine oxidoreductase. Uric acid …
converted to uric acid by an enzymatic reaction involving xanthine oxidoreductase. Uric acid …
[HTML][HTML] Reactive oxygen species and antioxidant defense in human gastrointestinal diseases
P Patlevič, J Vašková, P Švorc Jr, L Vaško… - Integrative medicine …, 2016 - Elsevier
Crohn's disease and ulcerative colitis, known together as inflammatory bowel diseases
(IBDs), and celiac disease are the most common disorders affecting not only adults but also …
(IBDs), and celiac disease are the most common disorders affecting not only adults but also …
Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation
A Ives, J Nomura, F Martinon, T Roger, D LeRoy… - Nature …, 2015 - nature.com
Activation of the NLRP3 inflammasome by microbial ligands or tissue damage requires
intracellular generation of reactive oxygen species (ROS). We present evidence that …
intracellular generation of reactive oxygen species (ROS). We present evidence that …