Vitamin E is an important natural antioxidant, and its most common and biologically active
form is α-tocopherol. In addition to this, specific regulatory effects of vitamin E have been …

αA-crystallin is a small heat-shock protein expressed preferentially in the lens and is
detected during the early stages of lens development. Recent work indicates that the …

The mammalian eye lens expresses a high concentration of crystallins (α, β and γ-
crystallins) to maintain the refractive index essential for lens transparency. Crystallins are …

PURPOSE: To identify and analyze differentially genes expressed between lens epithelia
dissected from age-related cataractous and noncataractous human lenses. METHODS …

Objective The incidence of after-cataracts [also known as posterior capsular opacification
(PCO)] is between 30% and 50% three years following cataract surgery. Suppressing the …

Purpose We have previously reported increased levels of Osteonectin/SPARC transcript in
age-related cataractous compared to normal human lenses. The purpose of the present …

Mice with deletion of genes for small heat shock proteins αA-and αB-crystallin (αA/αB–/–)
develop cataracts. We used proteomic analysis to identify lens proteins that change in …

Background αA-crystallin plays an important role in eye lens development. Its N-terminal
domain is implicated in several important biological functions. Mutations in certain …

Purpose: To characterize gene expression patterns between epithelia isolated from
cataractous and normal human lenses. Methods: Reverse transcriptase differential display …

Abstract Sir William Herschel's discovery of “obscure rays,” extending beyond the red end of
the visible spectrum, launched the exploration of the electromagnetic spectrum outside the …