Understanding asthma phenotypes, endotypes, and mechanisms of disease
ME Kuruvilla, FEH Lee, GB Lee - Clinical reviews in allergy & immunology, 2019 - Springer
The model of asthma as a single entity has now been replaced by a much more complex
biological network of distinct and interrelating inflammatory pathways. The term asthma is …
biological network of distinct and interrelating inflammatory pathways. The term asthma is …
Current understanding of asthma pathogenesis and biomarkers
N Habib, MA Pasha, DD Tang - Cells, 2022 - mdpi.com
Asthma is a heterogeneous lung disease with variable phenotypes (clinical presentations)
and distinctive endotypes (mechanisms). Over the last decade, considerable efforts have …
and distinctive endotypes (mechanisms). Over the last decade, considerable efforts have …
Treatable traits: toward precision medicine of chronic airway diseases
A Agusti, E Bel, M Thomas… - European …, 2016 - Eur Respiratory Soc
Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic
airway diseases that have a high personal and social impact. They likely represent a …
airway diseases that have a high personal and social impact. They likely represent a …
Global, regional, and national burden of allergic disorders and their risk factors in 204 countries and territories, from 1990 to 2019: A systematic analysis for the Global …
Background Asthma and atopic dermatitis (AD) are chronic allergic conditions, along with
allergic rhinitis and food allergy and cause high morbidity and mortality both in children and …
allergic rhinitis and food allergy and cause high morbidity and mortality both in children and …
What is asthma− COPD overlap syndrome? Towards a consensus definition from a round table discussion
Patients with asthma–chronic obstructive pulmonary disease overlap syndrome (ACOS)
have been largely excluded from pivotal therapeutic trials and, as a result, its treatment …
have been largely excluded from pivotal therapeutic trials and, as a result, its treatment …
Why has it taken so long for biological psychiatry to develop clinical tests and what to do about it?
Patients with mental disorders show many biological abnormalities which distinguish them
from normal volunteers; however, few of these have led to tests with clinical utility. Several …
from normal volunteers; however, few of these have led to tests with clinical utility. Several …
Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report
“Treatable traits” have been proposed as a new paradigm for the management of airway
diseases, particularly complex disease, which aims to apply personalised medicine to each …
diseases, particularly complex disease, which aims to apply personalised medicine to each …
[HTML][HTML] Adherence to inhaled therapies, health outcomes and costs in patients with asthma and COPD
MJ Mäkelä, V Backer, M Hedegaard, K Larsson - Respiratory medicine, 2013 - Elsevier
Suboptimal adherence to pharmacological treatment of asthma and chronic obstructive
pulmonary disease (COPD) has adverse effects on disease control and treatment costs. The …
pulmonary disease (COPD) has adverse effects on disease control and treatment costs. The …
Global burden of allergic bronchopulmonary aspergillosis with asthma and its complication chronic pulmonary aspergillosis in adults
DW Denning, A Pleuvry, DC Cole - Medical mycology, 2013 - academic.oup.com
Allergic bronchopulmonary aspergillosis (ABPA) complicates asthma and may lead to
chronic pulmonary aspergillosis (CPA) yet global burdens of each have never been …
chronic pulmonary aspergillosis (CPA) yet global burdens of each have never been …
COPD and its comorbidities: impact, measurement and mechanisms
NA Negewo, PG Gibson, VM McDonald - Respirology, 2015 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) frequently coexists with other conditions
often known as comorbidities. The prevalence of most of the common comorbid conditions …
often known as comorbidities. The prevalence of most of the common comorbid conditions …