Simple Summary Vincristine is a drug that is part of the treatment for many children with
cancer. Its main side-effect is vincristine-induced peripheral neuropathy (VIPN), which often …

The flavoenzyme N-ribosyldihydronicotinamide (NRH): quinone oxidoreductase 2 (NQO2)
catalyzes two-electron reductions of quinones. NQO2 contributes to the metabolism of …

N‐Nitrosamines are potent carcinogens and considered non‐threshold carcinogens in
various regulatory domains. However, recent data indicate the existence of a threshold for …

Food products simultaneously containing both food contaminants and emulsifiers are
common in baked products, coffee and chocolate. Little is known regarding how food …

Background Long-term survival induced by anticancer treatments discloses emerging frailty
among breast cancer (BC) survivors. Trastuzumab-induced cardiotoxicity (TIC) is reported in …

The objective of our study was to assess the effect of rumen-protected niacin
supplementation on the transcriptome of liver tissue in growing Angus× Simmental steers …

This study investigated an association between the cytochrome P450 (CYP) 2C8* 3
polymorphism with asthma symptom control in children and changes in lipid metabolism and …

Carboplatin is the cornerstone of ovarian cancer (OC) treatment, while platinum-response,
dependent on interindividual variability, is the major prognostic factor for long-term …

Cannabis-based products have seen increased usage in many parts of the world and in the
US, including increases in co-usage with tobacco products. This has led to a need for a …

Malaria constitutes a major public health concern in tropical and other malaria-endemic
regions. Genetic and non-genetic factors are known to in uence the pharmacokinetics and/or …