In the absence of effective interventions to prevent preterm births, improved survival of
infants who are born at the biological limits of viability has relied on advances in perinatal …

Recent studies have revealed biologically significant differences between human and
mouse lung development, and have reported new in vitro systems that allow experimental …

During late lung development, alveolar and microvascular development is finalized to
enable sufficient gas exchange. Impaired late lung development manifests as …

Regeneration of the architecturally complex alveolar niche of the lung requires precise
temporal and spatial control of epithelial cell behavior. Injury can lead to a permanent …

Bronchopulmonary dysplasia (BPD) is the most common respiratory disorder among infants
born extremely preterm. The pathogenesis of BPD involves multiple prenatal and postnatal …

Bronchopulmonary dysplasia (BPD) is the most common cause of morbidity and mortality in
preterm infants. A key histopathological feature of BPD is stunted late lung development …

Bronchopulmonary dysplasia (BPD) still carries a heavy burden of morbidity and mortality in
survivors of extreme prematurity. The disease is characterized by simplification of the …

Mesenchymal stem cells (MSCs) prevent the onset of bronchopulmonary dysplasia (BPD) in
animal models, an effect that seems to be mediated by their secreted extracellular vesicles …

Bronchopulmonary dysplasia (BPD) is the most common chronic morbidity in preterm
infants. In the absence of effective interventions, BPD is currently a major therapeutic …

Studies of human lung development have focused on epithelial and mesenchymal cell types
and function, but much less is known about the developing lung immune cells, even though …