Objective: The dramatic increase in the population with dementia expected in the next
decades is accompanied by the establishment of novel and innovated methods that will offer …

Dementia is characterized by the impairment of cognition and behavior of people over 65
years. Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder in the …

As a chronic metabolic disease, diabetes mellitus (DM) is broadly characterized by elevated
levels of blood glucose. Novel epidemiological studies demonstrate that some diabetic …

Increasing evidence suggests that abnormally hyperphosphorylated tau plays a vital role in
the pathogenesis of Alzheimer's disease (AD). Mitochondrial dysfunction also has a …

In the last few years, increased emphasis has been devoted to understanding the
contribution of mitochondria-associated endoplasmic reticulum (ER) membranes (MAM) to …

Alzheimer's disease (AD) is a debilitating neurodegenerative disorder characterized by the
progressive loss of cholinergic neurons, leading to the onset of severe behavioral, motor …

Despite intensive research efforts over the past few decades, the mechanisms underlying
the etiology of sporadic Alzheimer's disease (AD) remain unknown. This fact is of major …

Although, better known for its role in inflammation, the transcription factor nuclear factor
kappa B (NF-κB) has more recently been implicated in synaptic plasticity, learning, and …

Mitochondrial fragmentation due to fission/fusion imbalance has often been linked to
mitochondrial dysfunction and apoptosis in neurodegeneration. Conventionally, it is …

Beta amyloid (Aβ) is well accepted to play a central role in the pathogenesis of Alzheimer's
disease (AD). The present work evaluated the therapeutic effects of low-level laser …