Genetic and epigenetic alterations of familial pancreatic cancers

K Brune, SM Hong, A Li, S Yachida, T Abe… - … Biomarkers & Prevention, 2008 - AACR
Background: Little is known about the genetic and epigenetic changes that contribute to
familial pancreatic cancers. The aim of this study was to compare the prevalence of common …

MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine‐needle aspiration

DC Chhieng, E Benson, I Eltoum… - … Journal of the …, 2003 - Wiley Online Library
BACKGROUND Mucins are high molecular weight glycoproteins that are produced by
various epithelial cells including those found in the pancreas. MUC1 and MUC2 are two well …

[HTML][HTML] Next Generation Sequencing Improves the Accuracy of KRAS Mutation Analysis in Endoscopic Ultrasound Fine Needle Aspiration Pancreatic Lesions

D de Biase, M Visani, P Baccarini, AM Polifemo… - PloS one, 2014 - journals.plos.org
The use of endoscopic ultrasonography has allowed for improved detection and pathologic
analysis of fine needle aspirate material for pancreatic lesion diagnosis. The molecular …

Current status of diagnostic endoscopic ultrasonography in the evaluation of pancreatic mass lesions

T Itoi, A Sofuni, F Itokawa, A Irisawa… - Digestive …, 2011 - Wiley Online Library
Endoscopic ultrasonography (EUS) is currently well established as a diagnostic method for
the evaluation of pancreatic mass lesions. Diagnostic EUS might be divided into two broad …

Endoscopic ultrasound-guided fine-needle aspiration biopsy coupled with KRAS mutation assay to distinguish pancreatic cancer from pseudotumoral chronic …

B Bournet, A Souque, P Senesse, E Assénat… - …, 2009 - thieme-connect.com
Results: KRAS status analysis was successful in all EUS-FNAB samples. Codon-12 KRAS
point mutation was found in 66% of PADC samples. No case of chronic pancreatitis …

Endoscopic ultrasound fine needle aspirate DNA analysis to differentiate malignant and benign pancreatic masses

A Khalid, L Nodit, M Zahid, K Bauer… - Official journal of the …, 2006 - journals.lww.com
OBJECTIVES Accurate diagnosis of malignant and benign pancreatic masses can be
challenging, potentially delaying treatment for cancer and subjecting patients with benign …

[PDF][PDF] Use of IMP3 in identification of carcinoma in fine needle aspiration biopsies of pancreas

RK Yantiss, E Cosar, AH Fischer - Acta cytologica, 2008 - researchgate.net
Mar2008: Use of IMP3 in Identification of Carcinoma in Fine Needle Aspiration Biopsies of
Pancreas Page 1 Objective To evaluate insulin-like growth factor-II mRNA binding protein 3 …

Preoperative evaluation and management of the pancreatic head mass

C Conrad… - Journal of surgical …, 2013 - Wiley Online Library
The differential diagnosis of a pancreatic head mass encompasses a wide range of clinical
entities that include both solid and cystic lesions. This chapter focuses on our approach to …

[HTML][HTML] Clinical impact of K-ras mutation analysis in EUS-guided FNA specimens from pancreatic masses

T Ogura, K Yamao, A Sawaki, N Mizuno, K Hara… - Gastrointestinal …, 2012 - Elsevier
BACKGROUND: EUS-guided FNA (EUS-FNA) is considered optimal for differentially
diagnosing pancreatic masses. However, the sensitivity of EUS-FNA ranges from 65% to …

[HTML][HTML] Endoscopic Ultrasound–guided Fine-Needle Aspiration Biopsy Coupled With a KRAS Mutation Assay Using Allelic Discrimination Improves the Diagnosis of …

B Bournet, J Selves, D Grand, M Danjoux… - Journal of clinical …, 2015 - journals.lww.com
Results: Inconclusive or doubtful (low-grade dysplasia or atypia) cytopathology was found in
68 cases. Of these, 29 patients who had adenocarcinoma were subsequently diagnosed …