Endoscopic approach to early diagnosis of pancreatic cancer

N Fujita, Y Noda, G Kobayashi, K Kimura, K Ito - Pancreas, 2004 - journals.lww.com
Since its development, endoscopic retrograde cholangiopancreatography (ERCP) has been
playing a major role in the diagnosis of pancreatic diseases. The recent development of …

Molecular biologic approach to the diagnosis of pancreatic carcinoma using specimens obtained by EUS‐guided fine needle aspiration

K Kato, H Kamada, T Fujimori, Y Aritomo… - Gastroenterology …, 2012 - Wiley Online Library
We review the utility of endoscopic ultrasound‐guided fine needle aspiration (EUS‐FNA), a
rapid, safe, cost‐effective, and accurate diagnostic modality for evaluating pancreatic …

Effect of pancreatic juice cytology and/or endoscopic ultrasound‐guided fine‐needle aspiration biopsy for pancreatic tumor

K Matsumoto, Y Takeda, K Harada… - Journal of …, 2014 - Wiley Online Library
Abstract Background and Aim Endoscopic ultrasound‐guided fine‐needle aspiration biopsy
(EUS‐FNA) can now provide a cytopathological diagnosis of pancreatic malignancy with …

[HTML][HTML] Evaluation of S100A4 mRNA in EUS-FNA specimens for the assessment of chemosensitivity to gemcitabine from patients with unresectable pancreatic cancer

G Ma, Y Sun, S Fu - … Journal of Clinical and Experimental Pathology, 2015 - ncbi.nlm.nih.gov
Background/Aims: Gemcitabine (GEM) is the first-line chemotherapy in patients with
unresectable pancreatic cancer. However, the clinical outcomes of this regimen are still …

FNA smears of pancreatic ductal adenocarcinoma are superior to formalin‐fixed paraffin‐embedded tissue as a source of DNA: Comparison of targeted KRAS …

CP Hartley, AM Mahajan, SM Selvaggi… - Cancer …, 2017 - Wiley Online Library
BACKGROUND The current study was conducted to compare DNA yield, including
normalization to nuclear area, DNA amplification functionality, and detection of KRAS …

Diagnosing pancreatic malignancy in the setting of chronic pancreatitis: is there room for improvement?

JJ Farrell - Gastrointestinal endoscopy, 2005 - giejournal.org
Patients with chronic pancreatitis may present with clinical symptoms and radiographic
images that can be difficult to distinguish from pancreatic ductal adenocarcinoma. This …

[HTML][HTML] Detection of K-ras point mutation and telomerase activity during endoscopic retrograde cholangiopancreatography in diagnosis of pancreatic cancer

GX Zhou, JF Huang, ZS Li, GM Xu, F Liu… - World Journal of …, 2004 - ncbi.nlm.nih.gov
AIM: To study the value of monitoring K-ras point mutation at codon 12 and telomerase
activity in exfoliated cells obtained from pancreatic duct brushings during endoscopic …

Evolution and a promising role of EUS-FNA in gene and future analyses

M Kuwatani, N Sakamoto - Endoscopic Ultrasound, 2020 - journals.lww.com
Gene analysis with EUS‑FNA was firstly reported in 2001, which revealed the diagnosis of
gastrointestinal stromal tumors using mutational analysis of c‑kit.[1] Since the first report …

A meta-analysis of the diagnostic value of detecting K-ras mutation in pancreatic juice as a molecular marker for pancreatic cancer

J Yang, S Li, J Li, F Wang, K Chen, Y Zheng, J Wang… - Pancreatology, 2016 - Elsevier
Background K-ras codon 12 mutation is one of the earliest genetic changes in the
development of pancreatic cancer (PC) and accurate detection of K-ras mutations is gaining …

Endoscopic ultrasonography

A Chak - Endoscopy, 2000 - thieme-connect.com
After two decades of intensive clinical investigation, endo scopic ultrasonography (EUS) has
entered the new millen nium as an established technique in gastroenterology. En …