Abstract Since December 2019 the Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) has produced an outbreak of pulmonary disease which has soon become a …

The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

T cell responses play an important role in protection against beta-coronavirus infections,
including SARS-CoV-2, where they associate with decreased COVID-19 disease severity …

Identification of neoantigens is a critical step in predicting response to checkpoint blockade
therapy and design of personalized cancer vaccines. This is a cross-disciplinary challenge …

Introduction: Precision medicine is the concept of treating diseases based on environmental
factors, lifestyles, and molecular profiles of patients. This approach has been found to …

The identification of immunogenic neoantigens and their cognate T cells represents the most
crucial and rate-limiting steps in the development of personalized cancer immunotherapies …

Multi-epitope peptide vaccines, as a kind of fusion proteins, usually possess a string-of-
beads structure, consisting of several peptidic epitopes, probably adjuvants and linkers …

At the time of preparing this Perspective, large-scale vaccination for COVID-19 is in
progress, aiming to bring the pandemic under control through vaccine-induced herd …

APOBEC3B, an anti-viral cytidine deaminase which induces DNA mutations, has been
implicated as a mediator of cancer evolution and therapeutic resistance. Mutational plasticity …

Enterotoxigenic Bacteroides fragilis is an enteric pathogen which is described as a
causative agent of various intestinal infections and inflammatory diseases. Moreover …