Motile cilia are highly complex hair-like organelles of epithelial cells lining the surface of
various organ systems. Genetic mutations (usually with autosomal recessive inheritance) …

Life exists in three dimensions, but until the turn of the century most electron microscopy
methods provided only 2D image data. Recently, electron microscopy techniques capable of …

A finely regulated system of airway epithelial development governs the differentiation of
motile ciliated cells of the human respiratory tract, conferring the body's mucociliary …

Primary ciliary dyskinesia (PCD) is a rare multiorgan disease caused by genetic mutations
resulting in defects in motile cilia. Because cilia are responsible for clearing the secretions …

Cystic fibrosis (CF) and Primary ciliary dyskinesia (PCD) are both rare chronic diseases,
inherited disorders associated with multiple complications, namely respiratory …

Primary Ciliary Dyskinesia (PCD) is a rare, under-recognized disease that affects respiratory
ciliary function, resulting in chronic oto-sino-pulmonary disease. The PCD clinical phenotype …

Background and objectives Primary ciliary dyskinesia (PCD, ORPHA: 244) is a group of rare
genetic disorders characterized by dysfunction of motile cilia. It is phenotypically and …

Rationale: Primary ciliary dyskinesia (PCD) is a heterogeneous, multisystem disorder
characterized by defective ciliary beating. Diagnostic guidelines of the American Thoracic …

Primary ciliary dyskinesia (PCD) is an inherited cause of bronchiectasis. The estimated PCD
prevalence in children with bronchiectasis is up to 26% and in adults with bronchiectasis is 1 …

Background It is estimated that 1–13% of cases of bronchiectasis in adults globally are
attributable to primary ciliary dyskinesia (PCD) but many adult patients with bronchiectasis …