Ferroptosis is a novel regulated cell death pattern discovered when studying the mechanism
of erastin-killing RAS mutant tumor cells in 2012. It is an iron-dependent programmed cell …

Remote ischaemic conditioning (RIC) triggers endogenous protective pathways in distant
organs such as the kidney, heart and brain, and represents an exciting new paradigm in …

Background and Purpose—Treatment options for patients with acute ischemic stroke
depend on the volume of salvageable tissue. This volume assessment is currently based on …

Background and Purpose—Remote ischemic preconditioning is neuroprotective in models
of acute cerebral ischemia. We tested the effect of prehospital rPerC as an adjunct to …

Symptomatic intracranial arterial stenosis (SIAS) is very common in octo-and
nonagenarians, especially in the Chinese population, and is likely the most common cause …

In 1993, Przyklenk and colleagues made the intriguing experimental observation that 'brief
ischemia in one vascular bed also protects remote, virgin myocardium from subsequent …

Organ or tissue dysfunction due to acute ischemia–reperfusion injury (IRI) is the leading
cause of death and disability worldwide. Acute IRI induces cell injury and death in a wide …

Background and Purpose—Stroke imaging is pivotal for diagnosis and stratification of
patients with acute ischemic stroke to treatment. The potential of combining multimodal …

These preclinical findings launched a number of randomized clinical trials of remote limb
preconditioning to protect the heart. In a meta-analysis of 23 randomized clinical trials of …

Stroke is one of the main causes of neurological disability worldwide and the second cause
of death in people over 65 years old, resulting in great economic and social burden …