Neural tube closure: cellular, molecular and biomechanical mechanisms
Neural tube closure has been studied for many decades, across a range of vertebrates, as a
paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the …
paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the …
Neural tube defects
NDE Greene, AJ Copp - Annual review of neuroscience, 2014 - annualreviews.org
Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth
defects of the central nervous system that originate during embryonic development when the …
defects of the central nervous system that originate during embryonic development when the …
Neural tube defects—disorders of neurulation and related embryonic processes
AJ Copp, NDE Greene - Wiley Interdisciplinary Reviews …, 2013 - Wiley Online Library
Neural tube defects (NTDs) are severe congenital malformations affecting 1 in every 1000
pregnancies.'Open'NTDs result from failure of primary neurulation as seen in anencephaly …
pregnancies.'Open'NTDs result from failure of primary neurulation as seen in anencephaly …
Genetics of human neural tube defects
Neural tube defects (NTDs) are common, severe congenital malformations whose causation
involves multiple genes and environmental factors. Although more than 200 genes are …
involves multiple genes and environmental factors. Although more than 200 genes are …
An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure
MJ Harris, DM Juriloff - Birth Defects Research Part A: Clinical …, 2010 - Wiley Online Library
The number of mouse mutants and strains with neural tube defects (NTDs) now exceeds
240, including 205 representing specific genes, 30 for unidentified genes, and 9 …
240, including 205 representing specific genes, 30 for unidentified genes, and 9 …
Development of the vertebrate central nervous system: formation of the neural tube
NDE Greene, AJ Copp - Prenatal Diagnosis: Published in …, 2009 - Wiley Online Library
The developmental process of neurulation involves a series of coordinated morphological
events, which result in conversion of the flat neural plate into the neural tube, the primordium …
events, which result in conversion of the flat neural plate into the neural tube, the primordium …
Genetics of cleft lip and/or cleft palate: association with other common anomalies
N Setó-Salvia, P Stanier - European journal of medical genetics, 2014 - Elsevier
Cleft lip and/or cleft palate (CL/P) collectively are well known as being amongst the most
common birth defects but we still have difficulty explaining why the majority of cases occur …
common birth defects but we still have difficulty explaining why the majority of cases occur …
Mechanisms of tissue fusion during development
HJ Ray, L Niswander - Development, 2012 - journals.biologists.com
Tissue fusion events during embryonic development are crucial for the correct formation and
function of many organs and tissues, including the heart, neural tube, eyes, face and body …
function of many organs and tissues, including the heart, neural tube, eyes, face and body …
[HTML][HTML] Local protease signaling contributes to neural tube closure in the mouse embryo
We report an unexpected role for protease signaling in neural tube closure and the
formation of the central nervous system. Mouse embryos lacking protease-activated …
formation of the central nervous system. Mouse embryos lacking protease-activated …
Inositol, neural tube closure and the prevention of neural tube defects
NDE Greene, KY Leung, AJ Copp - Birth defects research, 2017 - Wiley Online Library
Susceptibility to neural tube defects (NTDs), such as anencephaly and spina bifida is
influenced by genetic and environmental factors including maternal nutrition. Maternal …
influenced by genetic and environmental factors including maternal nutrition. Maternal …