[PDF][PDF] Preliminary evidence of safety and tolerability of atezolizumab plus bevacizumab in patients with hepatocellular carcinoma and Child‐Pugh A and B cirrhosis: a …

A D'Alessio, CAM Fulgenzi, N Nishida… - …, 2022 - Wiley Online Library
Abstract Background and Aims Atezolizumab plus bevacizumab (AtezoBev) is the standard
of care for first‐line treatment of unresectable HCC. No evidence exists as to its use in …

[HTML][HTML] Efficacy and safety of atezolizumab and bevacizumab in the real-world treatment of advanced hepatocellular carcinoma: experience from four tertiary centers

V Himmelsbach, M Pinter, B Scheiner, M Venerito… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma is one of the most common cancers in the world
with increasing incidence. In advanced stages, according to the Barcelona Clinic Liver …

Early experience of atezolizumab plus bevacizumab therapy in Japanese patients with unresectable hepatocellular carcinoma in real-world practice

Y Hayakawa, K Tsuchiya, M Kurosaki, Y Yasui… - Investigational new …, 2022 - Springer
Background. We aimed to investigate the efficacy and safety of atezolizumab plus
bevacizumab therapy in patients with unresectable hepatocellular carcinoma (u-HCC) …

Comparison of atezolizumab plus bevacizumab and lenvatinib in terms of efficacy and safety as primary systemic chemotherapy for hepatocellular carcinoma

K Maesaka, R Sakamori, R Yamada, A Doi… - Hepatology …, 2022 - Wiley Online Library
Aim Atezolizumab plus bevacizumab and lenvatinib have each shown efficacy as primary
systemic chemotherapies for hepatocellular carcinoma (HCC) in clinical trials. However …

Does first‐line treatment have prognostic impact for unresectable HCC?—Atezolizumab plus bevacizumab versus lenvatinib

A Hiraoka, T Kumada, T Tada, M Hirooka… - Cancer …, 2023 - Wiley Online Library
Background/Aim A comparison of therapeutic efficacy between atezolizumab plus
bevacizumab (Atez/Bev) and lenvatinib treatment given as first‐line therapy for unresectable …

Safety and efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma in early clinical practice: a multicenter analysis

M Chuma, H Uojima, N Hattori, Y Arase… - Hepatology …, 2022 - Wiley Online Library
Purpose To assess the impact of clinical factors on the safety and efficacy of atezolizumab
plus bevacizumab (ATZ+ BV) treatment in patients with unresectable hepatocellular …

[HTML][HTML] Pretreatment neutrophil-to-lymphocyte ratio as a predictive marker of response to atezolizumab plus bevacizumab for hepatocellular carcinoma

Y Eso, H Takeda, K Taura, A Takai, K Takahashi… - Current …, 2021 - mdpi.com
Background: Combination therapy with anti-programmed death-ligand 1 monoclonal
antibody atezolizumab plus anti-vascular endothelial growth factor agent bevacizumab …

[HTML][HTML] Systemic treatment in intermediate stage (Barcelona Clinic Liver Cancer-B) hepatocellular carcinoma

DS Karagiannakis - Cancers, 2023 - mdpi.com
Simple Summary According to the latest BCLC algorithm, the reference treatment of BCLC-B
HCCs that are non-eligible for surgery or liver transplantation is trans-arterial …

[HTML][HTML] Early tumor response and safety of atezolizumab plus bevacizumab for patients with unresectable hepatocellular carcinoma in real-world practice

Y Ando, T Kawaoka, M Kosaka, Y Shirane, Y Johira… - Cancers, 2021 - mdpi.com
Simple Summary Although atezolizumab plus bevacizumab combination therapy was
approved in September 2020 as the first immune-combined therapy for hepatocellular …

Does immune checkpoint inhibitor exhibit limited efficacy against non‐viral hepatocellular carcinoma?: A review of clinical trials

Y Eso, K Taura, H Seno - Hepatology Research, 2022 - Wiley Online Library
Immunotherapy with immune checkpoint inhibitors has been shown to be beneficial for
cancers originating from various organs. In May 2020, combination therapy with anti …