Rett syndrome (RTT) is a postnatal neurodevelopmental disorder characterized by the loss
of acquired motor and language skills, autistic features, and unusual stereotyped …

Oxidatively generated damage to DNA has been implicated in the pathogenesis of a wide
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …

Background Triple-negative breast cancer (TNBC) is the most malignant subtype of breast
cancer with highly invasive ability and metastatic nature to the lymph nodes. Long non …

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide.
Several studies have identified signature gene sets that may be useful as potential …

Cell adhesion is a key regulator of cell differentiation. Cell interactions with neighboring cells
and the extracellular matrix regulate gene expression, cell proliferation, polarity and …

Senescence and altered differentiation potential of bone marrow stromal cells (BMSCs) lead
to age‐related bone loss. As an important posttranscriptional regulatory pathway, alternative …

Epithelial-mesenchymal transition (EMT) is a highly conserved morphogenic process
defined by the loss of epithelial characteristics and the acquisition of a mesenchymal …

Damage to RNA from ultraviolet light, oxidation, chlorination, nitration, and akylation can
include chemical modifications to nucleobases as well as RNA-RNA and RNA-protein …

The progressive maturation and functional plasticity of the nervous system in health and
disease involve a dynamic interplay between the transcriptome and the environment. There …

The mammalian AP-endonuclease (APE1/Ref-1) plays a central role in the repair of oxidized
and alkylated bases in mammalian genomes via the base excision repair (BER) pathway …