Programmed cell death protein 4 (PDCD4) has recently been shown to be involved in both
transcription and translation, and to regulate cell growth. However, the mechanisms …

Y-box (YB) protein-1 is secreted by mesangial and immune cells after cytokine challenge,
but extracellular functions are unknown. Here, we demonstrate that extracellular YB-1 …

The proto-oncogenes c-, L-, and N-myc can all be translated by the alternative method of
internal ribosome entry whereby the ribosome is recruited to a complex structural element …

Muscle atrophy with aging or disuse is associated with deregulated iron homeostasis and
increased oxidative stress likely inflicting damage to nucleic acids. Therefore, we …

Recent studies have uncovered an unanticipated diversity of noncoding RNAs (ncRNAs),
although these studies provide limited insight into their biological significance. Numerous …

The eukaryotic Y-box-binding protein-1 (YB-1) is involved in the transcriptional and
translational control of many biological processes, including cell proliferation. In clinical …

Human AP-endonuclease (APE1/Ref-1), a central enzyme involved in the repair of oxidative
base damage and DNA strand breaks, has a second activity as a transcriptional regulator …

Acute liver failure is characterized by the rapid development of liver dysfunction and
remarkably high mortality. Accumulating evidence suggests that soyasaponin possesses …

The overexpression of human apurinic/apyrimidinic (AP) endonuclease 1 (APE1/Ref-1), a
key enzyme in the DNA base excision repair (BER) pathway, is often associated with tumor …

In previous studies we identified the transcription/translation factor Y‐box‐binding protein
(YB‐1) as a gene that is upregulated in primary melanoma and melanoma metastases when …