Population stratification and spurious allelic association
Great efforts and expense have been expended in attempts to detect genetic polymorphisms
contributing to susceptibility to complex human disease. Concomitantly, technology for …
contributing to susceptibility to complex human disease. Concomitantly, technology for …
Linkage disequilibrium and association studies in higher plants: present status and future prospects
During the last two decades, DNA-based molecular markers have been extensively utilized
for a variety of studies in both plant and animal systems. One of the major uses of these …
for a variety of studies in both plant and animal systems. One of the major uses of these …
Genome-wide association studies: theoretical and practical concerns
WYS Wang, BJ Barratt, DG Clayton… - Nature Reviews Genetics, 2005 - nature.com
To fully understand the allelic variation that underlies common diseases, complete genome
sequencing for many individuals with and without disease is required. This is still not …
sequencing for many individuals with and without disease is required. This is still not …
Association study designs for complex diseases
Assessing the association between DNA variants and disease has been used widely to
identify regions of the genome and candidate genes that contribute to disease. However …
identify regions of the genome and candidate genes that contribute to disease. However …
Natural variation in Arabidopsis: from molecular genetics to ecological genomics
D Weigel - Plant physiology, 2012 - academic.oup.com
One of the most remarkable biological insights in the past 30 years has been that many
genetic programs for complex traits, such as flower or limb development, are shared across …
genetic programs for complex traits, such as flower or limb development, are shared across …
Haplotype blocks and linkage disequilibrium in the human genome
JD Wall, JK Pritchard - Nature Reviews Genetics, 2003 - nature.com
There is great interest in the patterns and extent of linkage disequilibrium (LD) in humans
and other species. Characterizing LD is of central importance for gene-mapping studies and …
and other species. Characterizing LD is of central importance for gene-mapping studies and …
Pseudomonas-Candida Interactions: An Ecological Role for Virulence Factors
DA Hogan, R Kolter - Science, 2002 - science.org
Bacterial-fungal interactions have great environmental, medical, and economic importance,
yet few have been well characterized at the molecular level. Here, we describe a pathogenic …
yet few have been well characterized at the molecular level. Here, we describe a pathogenic …
Metabolomics-assisted breeding: a viable option for crop improvement?
AR Fernie, N Schauer - Trends in genetics, 2009 - cell.com
Metabolomics approaches enable the parallel assessment of the levels of a broad range of
metabolites and have been documented to have great value in both phenotyping and …
metabolites and have been documented to have great value in both phenotyping and …
The Bayesian revolution in genetics
MA Beaumont, B Rannala - Nature Reviews Genetics, 2004 - nature.com
Bayesian statistics allow scientists to easily incorporate prior knowledge into their data
analysis. Nonetheless, the sheer amount of computational power that is required for …
analysis. Nonetheless, the sheer amount of computational power that is required for …
[PDF][PDF] Biometria aplicada ao estudo da diversidade genética
Esta obra visa proporcionar aos técnicos, pesquisadores e docentes conhecimentos
fundamentais para o estudo da diversidade genética. O leitor encontrará abordagem ampla …
fundamentais para o estudo da diversidade genética. O leitor encontrará abordagem ampla …