Great efforts and expense have been expended in attempts to detect genetic polymorphisms
contributing to susceptibility to complex human disease. Concomitantly, technology for …

During the last two decades, DNA-based molecular markers have been extensively utilized
for a variety of studies in both plant and animal systems. One of the major uses of these …

To fully understand the allelic variation that underlies common diseases, complete genome
sequencing for many individuals with and without disease is required. This is still not …

Assessing the association between DNA variants and disease has been used widely to
identify regions of the genome and candidate genes that contribute to disease. However …

One of the most remarkable biological insights in the past 30 years has been that many
genetic programs for complex traits, such as flower or limb development, are shared across …

There is great interest in the patterns and extent of linkage disequilibrium (LD) in humans
and other species. Characterizing LD is of central importance for gene-mapping studies and …

Bacterial-fungal interactions have great environmental, medical, and economic importance,
yet few have been well characterized at the molecular level. Here, we describe a pathogenic …

Metabolomics approaches enable the parallel assessment of the levels of a broad range of
metabolites and have been documented to have great value in both phenotyping and …

Bayesian statistics allow scientists to easily incorporate prior knowledge into their data
analysis. Nonetheless, the sheer amount of computational power that is required for …

Esta obra visa proporcionar aos técnicos, pesquisadores e docentes conhecimentos
fundamentais para o estudo da diversidade genética. O leitor encontrará abordagem ampla …