Challenges for identifying functionally important genetic variation: the promise of combining complementary research strategies
A Vasemägi, CR Primmer - Molecular Ecology, 2005 - Wiley Online Library
Strategies for the identification of functional genetic variation underlying phenotypic traits of
ecological and evolutionary importance have received considerable attention in the …
ecological and evolutionary importance have received considerable attention in the …
Corn and humans: recombination and linkage disequilibrium in two genomes of similar size
A Rafalski, M Morgante - TRENDS in Genetics, 2004 - cell.com
Two species with genomes of almost identical size, maize and human, have different
evolutionary histories, and as a result their genomes differ greatly in their content of …
evolutionary histories, and as a result their genomes differ greatly in their content of …
The genetics of variation in gene expression
VG Cheung, RS Spielman - Nature genetics, 2002 - nature.com
The genetic basis of variation in gene expression lends itself to investigation by microarrays.
For genetic analysis, we view the expression level of a gene as a quantitative …
For genetic analysis, we view the expression level of a gene as a quantitative …
Association analysis using SSR markers to find QTL for seed protein content in soybean
Association analysis studies can be used to test for associations between molecular markers
and quantitative trait loci (QTL). In this study, a genome-wide scan was performed using 150 …
and quantitative trait loci (QTL). In this study, a genome-wide scan was performed using 150 …
Parallel genotyping of over 10,000 SNPs using a one-primer assay on a high-density oligonucleotide array
H Matsuzaki, H Loi, S Dong, YY Tsai, J Fang… - Genome …, 2004 - genome.cshlp.org
The analysis of single nucleotide polymorphisms (SNPs) is increasingly utilizedto
investigate the genetic causes of complex human diseases. Here we present a high …
investigate the genetic causes of complex human diseases. Here we present a high …
A comprehensive review of the genetics of juvenile idiopathic arthritis
S Prahalad, DN Glass - Pediatric Rheumatology, 2008 - Springer
Juvenile idiopathic arthritis (JIA) is the most common chronic arthropathy of childhood which
is believed to be influenced by both genetic and environmental factors. The progress in …
is believed to be influenced by both genetic and environmental factors. The progress in …
Shaking the tree: mapping complex disease genes with linkage disequilibrium
Much effort and expense are being spent internationally to detect genetic polymorphisms
contributing to susceptibility to complex human disease. Concomitantly, the technology for …
contributing to susceptibility to complex human disease. Concomitantly, the technology for …
Population structure and breeding patterns of 145 US rice cultivars based on SSR marker analysis
H Lu, MA Redus, JR Coburn, JN Rutger… - Crop …, 2005 - Wiley Online Library
This study was undertaken to investigate the population structure of US rice (Oryza sativa
L.). A total of 115 US rice cultivars and 30 ancestral accessions introduced from Asia were …
L.). A total of 115 US rice cultivars and 30 ancestral accessions introduced from Asia were …
SNP association studies in Alzheimer's disease highlight problems for complex disease analysis
Genetic linkage and association analyses are two distinct approaches to understanding the
genetic etiology of complex disease. Association analysis has become particularly popular …
genetic etiology of complex disease. Association analysis has become particularly popular …
The Ph1 locus is needed to ensure specific somatic and meiotic centromere association
The correct pairing and segregation of chromosomes during meiosis is essential for genetic
stability and subsequent fertility. This is more difficult to achieve in polyploid species, such …
stability and subsequent fertility. This is more difficult to achieve in polyploid species, such …