Genetic association of complex traits: using idiopathic scoliosis as an example

JCY Cheng, NLS Tang, HY Yeung… - … and Related Research®, 2007 - journals.lww.com
Although the exact etiology of adolescent idiopathic scoliosis is still undefined, genetic
factors play an important role. Some patients have familial genetic disease that appears to …

Network biomarkers reveal dysfunctional gene regulations during disease progression

T Zeng, S Sun, Y Wang, H Zhu, L Chen - The FEBS journal, 2013 - Wiley Online Library
Extensive studies have been conducted on gene biomarkers by exploring the increasingly
accumulated gene expression and sequence data generated from high‐throughput …

Genome‐wide linkage and QTL mapping in porcine F2 families generated from Pietrain, Meishan and Wild Boar crosses

H Geldermann, E Müller, G Moser… - Journal of Animal …, 2003 - Wiley Online Library
Three informative pig F2 families based on European Wild Boar (W), Meishan (M) and
Pietrain (P) crosses have been used for genome‐wide linkage and quantitative trait loci …

A Multidisciplinary Approach Providing New Insight into Fruit Flesh Browning Physiology in Apple (Malus x domestica Borkh.)

M Di Guardo, A Tadiello, B Farneti, G Lorenz… - PLos one, 2013 - journals.plos.org
In terms of the quality of minimally processed fruit, flesh browning is fundamentally important
in the development of an aesthetically unpleasant appearance, with consequent off-flavours …

Linkage disequilibrium in cultivated grapevine, Vitis vinifera L

A Barnaud, T Lacombe, A Doligez - Theoretical and Applied Genetics, 2006 - Springer
We present here the first study of linkage disequilibrium (LD) in cultivated grapevine, Vitis
vinifera L. subsp. vinifera (sativa), an outcrossing highly heterozygous perennial species …

Linkage disequilibrium between loci with unknown phase

AR Rogers, C Huff - Genetics, 2009 - academic.oup.com
Linkage disequilibrium is often measured by two statistics, D and r, which can be interpreted
as the covariance and the correlation between loci and across gametes. When data consist …

[图书][B] Single nucleotide polymorphisms: methods and protocols

PY Kwok - 2008 - books.google.com
Single nucleotide polymorphisms (SNPs) have become the markers of choice in elucidating
the relationship between DNA sequence variation and susceptibility to disease and have …

Statistics for biology and health

M Gail, K Krickeberg, J Samet, A Tsiatis, W Wong - 2007 - Springer
Survival and event history analysis have developed into one of the major areas of
biostatistics, with important applications in other fields as well, including reliability theory …

One potato, two potato: haplotype association mapping in autotetraploids

I Simko - Trends in plant science, 2004 - cell.com
Potatoes are the world's most important vegetable and fourth most important food crop in
terms of production. Breeders try to develop new cultivars that combine yield, quality and …

Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion

K Ardlie, SN Liu-Cordero, MA Eberle, M Daly… - The American Journal of …, 2001 - cell.com
Understanding the pattern of linkage disequilibrium (LD) in the human genome is important
both for successful implementation of disease-gene mapping approaches and for inferences …