Cytokines, currently known to be more than 130 in number, are small MW (< 30 kDa) key
signaling proteins that modulate cellular activities in immunity, infection, inflammation and …

The links between anemia, iron deficiency (ID) and impaired hemodynamics were
suggested more than 50 years ago, but remained neglected. 1, 2 Chronic untreated anemia …

Bariatric surgeries such as the Vertical Sleeve Gastrectomy (VSG) are invasive but provide
the most effective improvements in obesity and Type 2 diabetes. We hypothesized a …

Prolyl hydroxylase (PH) enzymes control the degradation of hypoxia-inducible factor (HIF), a
transcription factor known to regulate erythropoiesis, angiogenesis, glucose metabolism, cell …

Erythropoietin, the primary regulator of erythropoiesis, is produced by the kidney and levels
vary inversely with oxygen availability. Hypoxia-inducible factor-1 (HIF-1), a major …

Background To provide multivariable prognostic models for severe complications prediction
after heart valve surgery, including low cardiac output syndrome (LCOS), acute kidney injury …

Sodium-glucose cotransporter-2 (SGLT2) inhibitors are currently the second-line
pharmacotherapy in type 2 diabetes, particularly through their effectiveness in reducing …

В многочисленных исследованиях установлено, что эритропоэтин (ЭПО) является
«универсальным» тканевым протекторным цитокином, а рецептор к ЭПО представлен …

This paper centers on some whole-istic organizational and functional aspects of hepatic
Schistosoma mansoni granuloma, which is an extremely complex system. First, it structurally …

Background Several cases of myopathies have been observed in the horse Norman Cob
breed. Muscle histology examinations revealed that some families suffer from a …