Advanced stages of cancer are highly associated with short overall survival in patients due
to the lack of long-term treatment options following the standard form of care. New options …

Checkpoint blockade antibodies have been approved as immunotherapy for multiple types
of cancer, but the response rate and efficacy are still limited. There are few immunogenic cell …

Stress granule (SG) assembly is a conserved cellular strategy to minimize stress-related
damage and promote cell survival. Beyond their fundamental role in the stress response …

The platinum-based drugs cisplatin, carboplatin, and oxaliplatin belong to the most widely
used chemotherapeutics in oncology, showing clinical efficacy against many solid tumors …

The expression “immunogenic cell death”(ICD) refers to a functionally unique form of cell
death that facilitates (instead of suppressing) a T cell-dependent immune response specific …

Recent progress in studying copper‐dependent targets and pathways in the context of tumor
treatment has provided new insights into therapeutic strategies of leveraging copper …

The immunogenic demise of cancer cells can be induced by various chemotherapeutics,
such as anthracyclines and oxaliplatin, and provokes an immune response against tumor …

The combination of relative nutrient deprivation and dysregulation of protein synthesis make
malignant cells especially prone to protein misfolding. Endoplasmic reticulum stress, which …

Paraptosis is characterized by the extensive vacuolization of endoplasmic reticulum (ER)
and mitochondria, which will cause the release of damage-associated molecular patterns to …

The traditional view holds that apoptosis is non-immunogenic and does not induce an
inflammatory response. However, recent studies have suggested that certain …