Prognostic and predictive impact of intra-and peritumoral immune infiltrates
WH Fridman, J Galon, F Pagès, E Tartour… - Cancer research, 2011 - AACR
Leukocyte infiltrates into or around tumor cell nests are found in the context of
protumorigenic inflammation and anticancer immunosurveillance. Hence, the detailed …
protumorigenic inflammation and anticancer immunosurveillance. Hence, the detailed …
PlatinER: A highly potent anticancer platinum (II) complex that induces endoplasmic reticulum stress driven immunogenic cell death
Immunogenic cell death (ICD) is a rare immunostimulatory form of cell death that can
improve the clinical outcomes of chemo‐immunotherapeutic combination regimens through …
improve the clinical outcomes of chemo‐immunotherapeutic combination regimens through …
[PDF][PDF] Immunogenic cell death.
Currently, it is widely acknowledged that a proactive anticancer immunosurveillance
mechanism takes part in the rejection of neoplastic lesions before they progress towards a …
mechanism takes part in the rejection of neoplastic lesions before they progress towards a …
Platinum (IV) antitumor complexes and their nano-drug delivery
C Jia, GB Deacon, Y Zhang, C Gao - Coordination Chemistry Reviews, 2021 - Elsevier
Platinum-based anticancer drugs dominate the chemotherapy field for several cancers, but
problems such as systemic toxicity and acquired resistance for some primary tumors hamper …
problems such as systemic toxicity and acquired resistance for some primary tumors hamper …
Chemotherapy‐induced immunogenic modulation of tumor cells enhances killing by cytotoxic T lymphocytes and is distinct from immunogenic cell death
Certain chemotherapeutic regimens trigger cancer cell death while inducing dendritic cell
maturation and subsequent immune responses. However, chemotherapy‐induced …
maturation and subsequent immune responses. However, chemotherapy‐induced …
Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells
CH Wu, J Li, L Li, J Sun, M Fabbri… - Journal of …, 2019 - Taylor & Francis
Extracellular vesicles (EVs) are secreted membrane vesicles, which play complex
physiological and pathological functions in intercellular communication. Recently, we …
physiological and pathological functions in intercellular communication. Recently, we …
Cardiac glycosides exert anticancer effects by inducing immunogenic cell death
L Menger, E Vacchelli, S Adjemian, I Martins… - Science translational …, 2012 - science.org
Some successful chemotherapeutics, notably anthracyclines and oxaliplatin, induce a type
of cell stress and death that is immunogenic, hence converting the patient's dying cancer …
of cell stress and death that is immunogenic, hence converting the patient's dying cancer …
Exploiting intrinsic nanoparticle toxicity: the pros and cons of nanoparticle-induced autophagy in biomedical research
1. INTRODUCTION In his 1959 keynote lecture “There is plenty of room at the bottom”,
Richard Feynman introduced the concepts that would later form the basis of a new era of …
Richard Feynman introduced the concepts that would later form the basis of a new era of …
Many faces of DAMPs in cancer therapy
A new concept of immunogenic cell death (ICD) has recently been proposed. The
immunogenic characteristics of this cell death mode are mediated mainly by molecules …
immunogenic characteristics of this cell death mode are mediated mainly by molecules …
Cisplatin and oxaliplatin induce similar immunogenic changes in preclinical models of head and neck cancer
Objectives Prior studies suggest that oxaliplatin is unique among platinum chemotherapy
drugs in its ability to enhance anti-tumor immunity, but the immune mechanisms of different …
drugs in its ability to enhance anti-tumor immunity, but the immune mechanisms of different …