Dysbiosis of Gut Microbiota from the Perspective of the Gut–Brain Axis: Role in the Provocation of Neurological Disorders

M Kandpal, O Indari, B Baral, S Jakhmola, D Tiwari… - Metabolites, 2022 - mdpi.com
The gut–brain axis is a bidirectional communication network connecting the gastrointestinal
tract and central nervous system. The axis keeps track of gastrointestinal activities and …

Lipopolysaccharides (LPSs) as potent neurotoxic glycolipids in Alzheimer's disease (AD)

Y Zhao, VR Jaber, AI Pogue, NM Sharfman… - International Journal of …, 2022 - mdpi.com
Lipopolysaccharides (LPSs) are microbiome-derived glycolipids that are among the most
potent pro-inflammatory neurotoxins known. In Homo sapiens, the major sources of LPSs …

[HTML][HTML] Extracellular vesicles derived from Porphyromonas gingivalis induce trigeminal nerve-mediated cognitive impairment

X Ma, YJ Shin, JW Yoo, HS Park, DH Kim - Journal of Advanced Research, 2023 - Elsevier
Introduction Porphyromonas gingivalis (PG)-infected periodontitis is in close connection with
the development of Alzheimer's disease (AD). PG-derived extracellular vesicles (pEVs) …

The gut-prostate axis: a new perspective of prostate cancer biology through the gut microbiome

K Fujita, M Matsushita, MA De Velasco, K Hatano… - Cancers, 2023 - mdpi.com
Simple Summary The gut microbiome plays important roles in the development of several
diseases. The gut microbiome is a dynamic system that is affected by several factors, such …

Selenium supplementation enhanced the expression of selenoproteins in hippocampus and played a neuroprotective role in LPS-induced neuroinflammation

X Liang, Z Xue, Y Zheng, S Li, L Zhou, L Cao… - International Journal of …, 2023 - Elsevier
Selenium (Se) is obtained from organic and inorganic selenium food content, which mainly
depends on the regional soil selenium content. Selenium deficiency and decreased …

P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress

A Verma, G Azhar, X Zhang, P Patyal, G Kc… - International Journal of …, 2023 - mdpi.com
Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, is associated with
neuroinflammation. Periodontal disease increases with age; 70.1% of adults 65 years and …

Nutrition in Alzheimer's disease: A review of an underappreciated pathophysiological mechanism

J Jiang, H Shi, S Jiang, A Wang, X Zou, Y Wang… - Science China Life …, 2023 - Springer
Alzheimer's disease (AD) is the leading cause of dementia in older individuals and is an
escalating challenge to global public health. Pharmacy therapy of AD is one of the well …

[HTML][HTML] Traditional Chinese medicine for the treatment of Alzheimer's disease: a focus on the microbiota–gut–brain axis

L Ma, X Jiang, Q Huang, W Chen, H Zhang… - Biomedicine & …, 2023 - Elsevier
Abstract Alzheimer's disease (AD), the most frequent cause of dementia, is a
neurodegenerative disorder characterised by a progressive decline in cognitive function that …

[HTML][HTML] Emerging relationship between the gut microbiome and prostate cancer

M Matsushita, K Fujita, K Hatano… - The World Journal of …, 2023 - ncbi.nlm.nih.gov
The human gut microbiota changes under the influence of environmental and genetic
factors, affecting human health. Extensive studies have revealed that the gut microbiome is …

Distinct post-sepsis induced neurochemical alterations in two mouse strains

CA Browne, G Clarke, P Fitzgerald, J O'Sullivan… - Brain, behavior, and …, 2022 - Elsevier
Sepsis associated encephalopathy, occurs in 70% of severe septic cases, following which
survivors exhibit long-term cognitive impairment or global loss of cognitive function …